Browse Studies — Arctuva

Phase 2

RETAIN: A Phase 2/3 Randomized, Placebo-Controlled Study to Evaluate the Efficacy of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Total Knee Arthroplasty (TKA)

The goal of this clinical trial is to evaluate whether the investigational drug PLG0206 can help reduce recurrence of infection in adults who have undergone to…

Prosthetic-joint Infection

Estimated

~$10 – $7,500

PeptilogicsNCT07214311

Observational

Durable, Real-component Antibiotic Spacers vs All-cement Articulating Spacers for the Treatment of Periprosthetic Knee Infection

In the US, if an infection in an artificial knee joint doesn't heal with antibiotics alone, the standard treatment is a two-stage revision of the artificial kn…

Prosthetic-joint InfectionKnee InfectionArthroplasty Complications+2 more

Estimated

~$10 – $6,250

Northwestern UniversityNCT06293352

Phase 1

Impact of Irrigation Volumes in Revision Total Knee Arthroplasty (TKA) Surgical Washout: A Pilot Study

The purpose of this pilot study is to determine the volume of irrigation required to achieve macroscopic clearance of contaminants during a debridement, antibi…

Total Knee ArthroplastyProsthetic-joint InfectionIrrigation

Estimated

~$10 – $6,250

University of MiamiNCT07324954

Observational

The Effect of Peri-Operative Adjunctive Probiotics on Immunological Markers in Cases of Prosthetic Joint Infection of the Hip and Knee

The purpose of this study is to determine whether probiotics in addition to standard of care (SOC) can improve immunological markers following treatment for pr…

Prosthetic-joint Infection

Estimated

~$10 – $7,500

NYU Langone HealthNCT06919913