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Clinical Genetics Branch (CGB) Eligibility Screening Survey
Background: Clinical Genetics Branch (CGB) researchers study individuals and populations at high genetic risk of cancer in order to improve our understanding …
MelanomaLi-Fraumeni SyndromePulmonary Blastoma+7 more
National Cancer Institute (NCI)NCT07005297
DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
Background: \- Pleuropulmonary blastoma (PPB) is a rare fast-growing lung tumor that is associated with other, rare tumor types. Most cases of PPB appear in c…
Pleuropulmonary BlastomaCystic NephromaOvarian Sertoli-Leydig Cell Tumors+2 more
National Cancer Institute (NCI)NCT01247597
Phase 3
Prospective Treatment of Types I, II and III Pleuropulmonary Blastoma (PPB)
This phase III trial tests how well surgery plus chemotherapy compared to surgery alone works in treating patients with type I pleuropulmonary blastoma (PPB), …
Pleuropulmonary Blastoma
Children's Oncology GroupNCT06647953
International Pleuropulmonary Blastoma/DICER1 Registry (for PPB, DICER1 and Associated Conditions)
Pleuropulmonary blastoma (PPB) is a rare malignant neoplasm of the lung presenting in early childhood. Type I PPB is a purely cystic lesion, Type II is a parti…
Pleuropulmonary BlastomaSertoli-Leydig Cell TumorDICER1 Syndrome+16 more
Children's Hospitals and Clinics of MinnesotaNCT03382158