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62 recruiting studies matching your filters

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass

Patients with pulmonary arterial hypertension (PAH) are at increased risk of muscle loss and decreased physical activity. This study will aim to (1) understand…

Pulmonary Hypertension

Estimated

~$10 – $750

University of PennsylvaniaNCT07132788

DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

This is a prospective, real world, multicenter, registry of patients with pulmonary hypertension associated with interstitial lung disease (PH-ILD) and interst…

Pulmonary Hypertension Due to Lung Diseases and HypoxiaPulmonary HypertensionInterstitial Lung Disease

Estimated

~$10 – $1,050

United TherapeuticsNCT06388421

Observational

Target Oxygen Saturation Ranges in Infants With Bronchopulmonary Dysplasia Associated Pulmonary Hypertension

Around 50% of infants born extremely preterm develop a chronic lung disease known as bronchopulmonary dysplasia of which some infants will also develop pulmona…

Bronchopulmonary DysplasiaPulmonary Hypertension

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT06373289

Deep Learning for Algorithmic Detection of Pulmonary Hypertension Using a Combined Digital Stethoscope and Single-lead Electrocardiogram

The major goal of the study is to determine whether phonocardiography (using the Eko DUO stethoscope which can capture a three lead ECG reading) can present fe…

Pulmonary Hypertension

Estimated

~$10 – $1,050

Eko Devices, Inc.NCT05873387

Phase 3

A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction

The purpose of this study is to assess the efficacy and safety of the study drug, levosimendan (given orally), compared to placebo in participants with pulmona…

Pulmonary Hypertension Associated With HFpEF

Estimated

~$10 – $8,750

Tenax Therapeutics, Inc.NCT07288398

Phase 4

Dopamine vs. Norepinephrine in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure and Systemic Hypotension Due to Pulmonary Hypertension: A Pilot Trial

This pilot randomized clinical trial compares dopamine and norepinephrine as first-line vasoactive therapies in term and late preterm neonates with pulmonary h…

Hypotension and ShockPulmonary Hypertension of the Newborn (PPHN)Hypoxemic Respiratory Failure

Estimated

~$10 – $6,250

University of California, DavisNCT07322133

Phase 2

Autologous Stem Cell Transplantation With CD34-Selected Peripheral Blood Stem Cells (PBSC) in Patients With Treatment Resistant Systemic Sclerosis (SSc)

The purpose of this study is to determine whether a regimen of high-dose immunoablative therapy will demonstrate safety that is consistent or improved with oth…

Systemic SclerosisDiffuse Sclerosis SystemicInterstitial Lung Disease+1 more

Estimated

~$10 – $7,500

Paul SzabolcsNCT03630211

Phase 3

A Long-term Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder for Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease

The primary objective of this study is to evaluate the safety and tolerability of the long-term use of TPIP in participants with PH-ILD from Study INS1009-311 …

Pulmonary HypertensionInterstitial Lung Disease

Estimated

~$10 – $8,750

Insmed IncorporatedNCT07234032

Phase 2

A Phase 2A, Open-Label Single Arm Multicenter Exploratory Study to Evaluate the Safety, Tolerability, and Efficacy of Oral Doses of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH).

This study evaluates the effect of ROC-101 in adults with either Pulmonary Arterial Hypertension (PAH) or Pulmonary Hypertension Associated with Interstitial L…

Pulmonary Arterial Hypertension (PAH)Pulmonary Hypertension, Interstitial Lung Disease

Estimated

~$10 – $8,750

AllRock Bio, Inc.NCT07175038

Phase 2

Xenon MRI in Pulmonary Hypertension

The overall objective outlined in this study is to determine how pulmonary vascular remodeling in PAH at a cellular and pathological level is associated with c…

Pulmonary HypertensionPulmonary Arterial Hypertension

Estimated

~$10 – $7,500

Bastiaan DriehuysNCT04991454

Phase 1

A Pilot Study of Transseptal ECMO With the Protek Solo Cannula in Lung Transplant Candidates With Right Heart Failure From Pulmonary Hypertension

The purpose of this study is to determine if transseptal extra-corporeal membrane oxygenation (ECMO) can bridge pulmonary hypertension- right heart failure (PH…

Lung TransplantPulmonary Hypertension

Estimated

~$10 – $6,250

Mayo ClinicNCT06770023

Observational

The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease

This study evaluates the effects of a structured home exercise program in participants with pulmonary hypertension associated with interstitial lung disease. P…

Pulmonary HypertensionInterstitial Lung Disease

Estimated

~$10 – $6,250

University of RochesterNCT07561034