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3 recruiting studies matching your filters
Phase 1
A Randomized Phase I/II Study of Talazoparib or Temozolomide in Combination With Onivyde in Children With Recurrent Solid Malignancies and Ewing Sarcoma
The phase I portion of this study is designed for children or adolescents and young adults (AYA) with a diagnosis of a solid tumor that has recurred (come back…
Recurrent Solid TumorRecurrent Ewing SarcomaRecurrent Hepatoblastoma+19 more
St. Jude Children's Research HospitalNCT04901702
Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Hepatic Tumors Research Consortium Initiative
There are limited data regarding the biology and treatment of relapsed/refractory hepatoblastoma (rrHBL). This project provides the infrastructure for acquisit…
Relapsed HepatoblastomaRefractory Hepatoblastoma
Children's Hospital Medical Center, CincinnatiNCT05556642
Phase 1
A Phase 1/2 Study of Tegavivint (NSC#826393) in Children, Adolescents, and Young Adults With Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come b…
Colorectal CarcinomaEndometrial CarcinomaMelanoma+19 more
Children's Oncology GroupNCT04851119