Browse studies

Find your next paid study

40 recruiting studies matching your filters

Phase II Clinical Trial Evaluating the Safety Efficacy of Fc-Modified Anti-CD154 mAB (TNX-1500) in Kidney Transplant Recipients

The primary objective is to investigate the safety of TNX-1500, an FC-modified anti-CD154 mAb, in five kidney transplant recipients at 12 months.

Kidney TransplantKidney Transplant Failure and RejectionImmunosuppression+1 more

Estimated

~$10 – $7,500

Ayman Al Jurdi, MDNCT07204080

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

This study aims to develop and refine a microRNA (miR) biomarker panel that can be used to phenotype net immune state after heart transplantation using circula…

Cardiac FailureGraft Rejection

Estimated

~$10 – $750

Northwestern UniversityNCT06939751

Phase 1

Targeting the B Cell Response to Treat Antibody-Mediated Rejection With Carfilzomib and Belatacept (CarBel)

The purpose of this study is to evaluate the safety of carfilzomib and belatacept, administered with steroids and maintenance immunosuppression, in kidney tran…

Kidney Transplant Rejection

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT06918990

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes: PROMISE-Lung Study

This project aims to collect detailed clinical data, blood samples, and patient-reported outcomes from 2,600 lung transplant candidates, donors, and recipients…

Lung Transplant; ComplicationsLung Transplant; Infection or InflammationLung Transplant Rejection+1 more

Estimated

~$10 – $750

Duke UniversityNCT06399302

GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chronic Rejection in Lung Transplantation

Background: Lung transplants can save lives, but the procedure has risks. Some people develop donor-specific antibodies (DSA) after the procedure-that is, the…

Lung TransplantEnd Stage Lung DiseaseRejection

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT07516379

Observational

Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients: Enhancing Technological Innovation and Strengthening the Role of Small Businesses in Meeting Needs of Adolescent Organ Transplant

We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nona…

Heart Transplant RejectionImmune SuppressionPediatric Heart Transplant+4 more

Estimated

~$10 – $6,250

University of FloridaNCT05732779

Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLAD

This study is for people who have had a lung transplant and developed a condition called chronic lung allograft dysfunction (CLAD), which is a type of chronic …

Lung Transplant Failure and RejectionCLAD, Bronchiolitis ObliteransExtracorporeal Photopheresis

Estimated

~$10 – $1,125

Brian KellerNCT07434869

Outcome Reflection for Immune Mediated Rejection by Utilizing Artificial Intelligence in Cardiac Transplant Patients Through Early and Late Echocardiographic Analysis (ORACLE)

The purpose of this research is to detect episodes of rejection versus non-rejection after cardiac transplant and the diagnostic accuracy of an Artificial Inte…

Cardiac Transplant Rejection

Estimated

~$10 – $750

Mayo ClinicNCT06178744

Multi-Centric Observational Study to Analyze the Diagnostic Molecular Features in the Clinical Setting of Lung Allograft Biopsies

Objective: To evaluate the potential impact of molecular phenotyping of transbronchial biopsies in lung transplant recipients with allograft dysfunction, and t…

Lung Transplant Rejection

Estimated

~$10 – $750

University of AlbertaNCT02812290

Trifecta-Heart cfDNA-MMDX Study: Comparing the DD-cfDNA Test to MMDx Microarray Test and Central HLA Antibody Test

Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood transplant recipient and the Molecular Microscope® (MMDx) Diagnostic System re…

Heart Transplant Rejection

Estimated

~$10 – $750

University of AlbertaNCT04707872

Evaluating Urinary CXCL10 for Enhanced Detection of Acute Rejection in Kidney Transplant Patients With Low DD-CFDNA: Diagnostic Performance and Transport Stability Across Shipping Conditions (CLEAR-CXCL10)

Kidney transplant rejection remains a significant challenge to long-term graft survival. While histological biopsy continues to be the gold standard for diagno…

Kidney Transplant Rejection

Estimated

~$10 – $750

Virginia Commonwealth UniversityNCT07415876

Trifecta-Kidney cfDNA-MMDx Study: Comparing the DD-cfDNA Test to MMDx Microarray Test, Central HLA Antibody Test, and Histology.

Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood, and the Molecular Microscope® (MMDx) Diagnostic System results in indication …

Kidney Transplant Rejection

Estimated

~$10 – $750

University of AlbertaNCT04239703