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4 recruiting studies matching your filters
Phase 1
First-in-Human Study of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell Carcinoma
This study is being done to determine if the investigational radiotracer called 111In-XYIMSR-01 is helpful in detecting clear cell renal cell carcinoma tissue …
Renal Cell Carcinoma (Kidney Cancer)
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT07062549
Observational
Pilot Study Assessment of Bone Mineral Density Changes During Treatment With Anti-PD-1 Immunotherapy Agents
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and work by blocking protein interactions that normally prevent the immune system from…
Breast Cancer (Triple Negative Breast Cancer (TNBC))Renal Cell Carcinoma (Kidney Cancer)Melanoma (Skin Cancer)+5 more
Jessica Mezzanotte SharpeNCT07555210
An Observational Study Obtaining Solid Tumor Tissue From Participants and Apheresis for CAR T-Cell Therapy Manufacturing
Objective: To collect information on how often a solid tumor cancer might lose the Human Leukocyte Antigen (HLA) by next generation sequencing and perform aph…
Solid Tumor, AdultColorectal CancerNon Small Cell Lung Cancer+14 more
A2 Biotherapeutics Inc.NCT04981119
Phase 1
Phase 1, First-in-Human, Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of KO-2806 When Administered as Monotherapy and in Combination Therapy in Adult Patients With Advanced Solid Tumors
This first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyltransferase inhibitor (FTI), as a monotherapy and …
Solid Tumors With HRAS AlterationsNon Small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)+4 more
Kura Oncology, Inc.NCT06026410