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Phase 1
A Phase Ib Open Label Clinical Trial to Evaluate the Safety and Efficacy of ERAS-801 in Surgically Accessible Recurrent Glioblastoma Patients With EGFR Amplification or Mutation (ERAS801-SARG)
This phase Ib trial tests the safety and side effects of ERAS-801 in treating patients with isocitrate dehydrogenase (IDH) wildtype, epidermal growth factor re…
IDH Wildtype GlioblastomaRecurrent AstrocytomaIDH Wildtype Recurrent Glioblastoma+2 more
Jonsson Comprehensive Cancer CenterNCT07089641
Phase 2
MC230719 Window Of Opportunity Study Of GI-102 In Patients With Recurrent High-Grade Glioblastoma
This phase II trial compares the effect of GI-102 alone and in combination with pembrolizumab given before surgery in treating patients with IDH wildtype gliob…
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo ClinicNCT07301268
Observational
Exploration Into the Association Between Decorin (DCN) Expression and MR Phenotypes in GBM
This clinical trial uses a type of imaging scan called magnetic resonance imaging (MRI) to study brain tumor biology in patients with glioblastoma that can be …
GlioblastomaRecurrent GlioblastomaResectable Glioblastoma
Jonsson Comprehensive Cancer CenterNCT06090903