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177 recruiting studies matching your filters

A Phase 1/2A, Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 (hCitH3-mAb) in Healthy Volunteers and in Patients With Mild-to-Moderate ARDS: Part A (Healthy Volunteers)

This Phase 1/2A, randomized, double-blind study will evaluate the safety, tolerability, and pharmacokinetics (PK) of HT31-1 (hCitH3-mAb) in healthy adult volun…

ARDS (Acute Respiratory Distress Syndrome)

A Clinical Trial Comparing Surfactant Administration Through Supraglottic Airway or Thin Catheter for Preterm Infants

What is this study about? This study is comparing two ways of giving surfactant, a medicine that helps premature infants breathe better. Surfactant can be give…

SurfactantRespiratory Distress Syndrome (Neonatal)

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT07030270

Phase 1

Assessing Pulmonary Changes in Hematopoietic Stem-Cell Transplantation Patients and Patients With Rare-Lung Diseases Using Hyperpolarized Xe MR Lung Imaging

This will be an un-blinded, open-label study of children and adults, including those who are being evaluated for or who have undergone HSCT, those with existin…

HSCTRespiratoryGas Exchange Impairment

Estimated

~$10 – $5,625

Children's Hospital Medical Center, CincinnatiNCT07823036

Observational

Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS)

The purpose of this project is to reduce maternal environmental exposures to toxicants through a patient education program designed to help pregnant women lear…

Environmental ExposurePregnancy RelatedPreterm Birth+2 more

Estimated

~$10 – $6,250

The University of Texas Medical Branch, GalvestonNCT07758114

Lung and Heart Function Across Decades of Life in Healthy Population

The main objective of this study is to develop baseline "normal" reference values of both lung and heart function for healthy adults within the age range relev…

Estimated

~$10 – $675

University of California, San FranciscoNCT07641413

Phase 1

Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration

The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal populati…

Respiratory Disorders

Estimated

~$10 – $5,625

Children's Hospital Medical Center, CincinnatiNCT02316379

Phase 2

A Randomized, Double-Blind, Two-Part, Placebo-Controlled, Multicenter, Phase 2a Study to Evaluate Safety, Tolerability, and Efficacy of INNA-051 as Prophylaxis for Respiratory Tract Illness in Healthy Adults 18 to 45 Years of Age Who Are at Risk for Viral Respiratory Infections

Acute upper and lower respiratory infections are a major public health problem and a leading cause of morbidity and mortality worldwide. The purpose of this tr…

Viral Respiratory InfectionViral Respiratory Illnesses

Estimated

~$10 – $8,750

ENA Respiratory Pty LtdNCT07222670

Phase 2

A Phase 2 Randomized Double-blind Placebo-controlled Study To Evaluate The Efficacy And Safety Of Adjunctive Recombinant Human Plasma Gelsolin With Standard Care For Moderate-to-Severe ARDS Due To Pneumonia Or Other Infections

BTI-203 is a randomized, double-blind, placebo-controlled, multicenter, Phase 2 proof-of-concept (POC) study to evaluate the efficacy and safety of rhu-pGSN pl…

Acute Respiratory Distress SyndromeInfections

Estimated

~$10 – $8,750

BioAegis Therapeutics Inc.NCT05947955

Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies

Background: Respiratory viruses circulate throughout the year and around the globe. Wearable and sensor devices, like smartwatches, may be able to help monito…

InfluenzaRespiratory VirusCoronavirus

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT04772170

Estimating the Risk for and Severity of Respiratory Infections Attributable to CFTR Heterozygosity

A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to pe…

Carrier StateRespiratory Infections

Estimated

~$10 – $1,125

Philip PolgreenNCT05474430

Phase 1

Development and Evaluation of a Host Pathologic State-Directed Botanical Therapeutic Platform Technology for Acute Viral Respiratory Infection

This Phase 1 study will evaluate the feasibility and safety of implementing a host pathologic state-directed botanical therapeutic platform in adults with acut…

Acute Viral Respiratory Infection

Estimated

~$10 – $6,250

All Natural Medicine Clinic, LLCNCT07805447

Observational

Pilot Trial Evaluating a Mechanical Power Targeted Ventilation Strategy in Adult VV ECMO Patients With Severe ARDS

The purpose of this study is to find a better way to protect the lungs of patients with Acute Respiratory Distress Syndrome (ARDS) who are being treated with a…

ARDS (Acute Respiratory Distress Syndrome)VV ECMO

Estimated

~$10 – $6,250

University of VirginiaNCT07790133