Browse Studies — Arctuva

Phase 2

Nemtabrutinib and Pembrolizumab in Patients With Richter Transformation: A Phase II Study

This phase II trial tests how well nemtabrutinib in combination with pembrolizumab works in treating patients with Richter transformation, diffuse large B-cell…

Richter SyndromeDiffuse Large B-Cell LymphomaChronic Lymphocytic Leukemia

Estimated

~$10 – $7,500

Roswell Park Cancer InstituteNCT06863402

Phase 1

A Phase I Study of Covalent BTK Inhibitor Zanubrutinib in Combination With a CD3-CD20 Bispecific Antibody Odronextamab in Patients With Richter's Transformation

This phase I trial tests the safety and side effects of zanubrutinib in combination with odronextamab and how well it works in treating patients with Richter's…

Recurrent Transformed Chronic Lymphocytic LeukemiaRefractory Transformed Chronic Lymphocytic LeukemiaRichter Syndrome+1 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT06735664

Phase 1

Safety and Tolerability of Myeloablative Conditioning and Autologous Stem Cell Transplantation Followed by Polatuzumab Vedotin (PV) Immunoconjugate Therapy in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma

Patients will receive one of two conditioning regimens (BEAM or CBV) before receiving an autologous stem cell transplant (ASCT). If patients achieve either com…

B-cell LymphomaBurkitt LymphomaDiffuse Large B Cell Lymphoma+6 more

Estimated

~$10 – $6,250

New York Medical CollegeNCT04491370

Phase 2

MC198B, Phase II Study of a Combination Therapy of Acalabrutinib, Venetoclax and Durvalumab in Patients With Richter Transformation From Chronic Lymphocytic Leukemia (CLL)

This phase II trial tests whether acalabrutinib, venetoclax, and durvalumab work in treating patients with Richter transformation from chronic lymphocytic leuk…

Chronic Lymphocytic LeukemiaRichter SyndromeSmall Lymphocytic Lymphoma

Estimated

~$10 – $6,250

Mayo ClinicNCT05388006