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Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
Durable left ventricular assist devices (dLVAD) have been increasingly utilized since the mid to late 1990s, with an uptick of utility starting in 2010 followi…
LVADFrailtyGI Bleed+5 more
International Consortium of Circulatory Assist CliniciansNCT06039176
Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure
Right ventricular (RV) failure is recognized to worsen patient outcomes in the setting of heart failure with reduced ejection fraction (HFrEF)-related pulmonar…
Heart Failure With Reduced Ejection FractionPulmonary HypertensionRight Heart Failure Due to Left Heart Failure
Johns Hopkins UniversityNCT06299436
Hepatic Perfusion and Liver Health as Assessed by Dual Cholate Clearance Assay in Fontan-associated Liver Disease (FALD)
The goal of this study is to use the HepQuant dual cholate clearance assay, which has been shown to measure liver function in people with known chronic liver c…
FontanRight Heart Failure
HepQuant, LLCNCT07009132
Phase 2
Repurposing Valsartan May Protect Against Pulmonary Hypertension
This is a Phase 2, single-center, randomized placebo controlled trial of valsartan (an angiotensin receptor blocker) in adults with pulmonary arterial hyperten…
Pulmonary Arterial HypertensionRight Heart FailureRight Ventricular Dysfunction+1 more
University of WashingtonNCT06053580