The purpose of this study is to see if treatment with mirdametinib in patients with Langerhans cell histiocytosis (LCH) or other histiocytic disorders will be …

Langerhans Cell Histiocytosis (LCH)Juvenile Xanthogranuloma (JXG)Rosai-Dorfman Disease (RDD)+1 more

~Estimated

~$10 – $5,625

Children's Hospital Medical Center, CincinnatiNCT06153173

Phase 1

In-human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

The purpose of this study is to determine the uptake of the imaging agent \[68Ga\]-pentixafor with PET/CT scans in people with monoclonal gammopathy of undeter…

Non-Hodgkin LymphomaMultiple MyelomaHistiocytic Neoplasms+2 more

~Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT05093335

International Rare Histiocytic Disorders Registry (IRHDR)

The rare histiocytic disorders (RHDs) are characterized by the infiltration of one or more organs by non-LCH histiocytes. They can range from localized disease…

Rare Histiocytic Disorders (RHDs)Erdheim-Chester Disease (ECD)Rosai-Dorfman Disease (RDD)+7 more

~Estimated

~$10 – $750

The Hospital for Sick ChildrenNCT02285582