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4 recruiting studies matching your filters
Phase 1
Study of Intratumoral Injections of VLPONC-01 in Head and Neck Cancer
The goal of this clinical trial is to assess the safety and tolerability of a virus replicon particle (VRP) encapsulated saRNA encoding IL-12 when injected int…
Head and Neck Cancers- Squamous CellHead and Neck CancerSolid Tumors+10 more
VLP TherapeuticsNCT06736379
Phase 1
Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC)
This is a phase 1, open-label, single-center study that plans to enroll 40 participants who will undergo surgical resection as SOC for HNSCC. This trial is des…
HnsccHead and NeckSquamous Cell Cancer+8 more
Vanderbilt-Ingram Cancer CenterNCT07460765
Phase 1
A Phase 1 Dose-Escalation Study of SLV-154 in Subjects With Metastatic Solid Tumors
This is a Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of SLV-154 across a range of do…
Squamous Cell Cancer of Head and Neck (SCCHN)NSCLCSCLC+7 more
Solve TherapeuticsNCT06771219
Observational
Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy for Pain Palliation in Head, Neck, & Brachial Cancer
This phase 1 multi-site study investigates the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, …
Head Neck CancerSquamous Cell Cancer of Head and Neck (SCCHN)Cancer Pain
University of VirginiaNCT07405645