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816 recruiting studies matching your filters

Cancer CARE Beyond Walls - A Pilot of a Randomized, Pragmatic Trial of Cancer Directed Therapy Administration in the Patients' Homes Versus in Clinic

This clinical trial studies the effect of cancer directed therapy given at-home versus in the clinic for patients with cancer that may have spread from where i…

Advanced Anal CarcinomaAdvanced Biliary Tract CarcinomaAdvanced Bladder Carcinoma+41 more

Estimated

~$10 – $6,250

Mayo ClinicNCT05969860

Phase 3

A Randomized, Double-Blind, Placebo-Controlled, Multi-Regional Phase III Clinical Study of Toripalimab Alone or in Combination With Tifcemalimab (JS004/TAB004) as Consolidation Therapy in Patients With Limited-Stage Small Cell Lung Cancer Without Disease Progression Following Chemoradiotherapy

The Study is a Phase 3, randomized, three-arm, double-blind, placebo-controlled, multi-regional clinical research study to evaluate the safety and efficacy use…

Limited-stage Small Cell Lung Cancer (LS-SCLC)

Estimated

~$10 – $8,750

Shanghai Junshi Bioscience Co., Ltd.NCT06095583

Experiences With and Attitudes Towards Immune Checkpoint Inhibitors in Patients With Non-Small Cell Lung Cancer (NSCLC) - A Single Center, Survey-Based Study

This study evaluates patient satisfaction with receiving intravenous (IV) and/or subcutaneous (SC) immunotherapy and to assess patient preference for IV immuno…

Lung Non-Small Cell Carcinoma

Estimated

~$10 – $750

University of Southern CaliforniaNCT07339254

Observational

Bronchoscopy With and Without Needle-based Confocal Laser Endomicroscopy for Peripheral Lung Nodule Diagnosis: Protocol for a Multicenter Randomized Controlled Trial (CLEVER Trial)

The goal of this multi-center randomized clinical trial is to evaluate the added value of needle based confocal laser endomicroscopy (nCLE)-imaging to regular …

Lung CancerLung Neoplasm MalignantCarcinoma, Non-Small-Cell Lung+1 more

Estimated

~$10 – $6,250

Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)NCT06079970

Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies

This study examines the quality of life in patients with monoclonal gammopathy of unknown significance and smoldering multiple myeloma. Collecting quality of l…

Monoclonal Gammopathy of Undetermined SignificanceSmoldering Plasma Cell Myeloma

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT05136807

Phase 1

A First-In-Human Phase 1/2 Open-Label Study of Intravenous ST-067, Subcutaneous ST-067 with or Without Obinutuzumab Pre-Treatment, and ST-067 in Combination with Pembrolizumab in Subjects with Advanced Solid Malignancies

This is a multiphase, multicenter study, which includes a Phase 1a open-label, dose escalation monotherapy study of ST-067 given as an SC injection with or wit…

CancerSolid TumorMelanoma+6 more

Estimated

~$10 – $8,750

Simcha IL-18, Inc.NCT04787042

Phase 2

Use of Isatuximab, Dexamethasone and Lenalidomide in a Go-Slow Fashion for Ultra-Frail Patients With Multiple Myeloma: A Phase 2 Multicenter Study

Historically, the frailest patients with multiple myeloma are under-represented in clinical trials, and have very high rates of treatment discontinuation, and …

Multiple MyelomaPlasma Cell Leukemia

Estimated

~$10 – $6,250

University of UtahNCT06517017

Phase 3

A Phase III, Open-label, Randomised Study of Osimertinib With or Without Datopotamab Deruxtecan (Dato-DXd), as First-line Treatment in Participants With Epidermal Growth Factor Receptor (EGFR) Mutation-positive, Locally Advanced or Metastatic Non-small Cell Lung Cancer

The purpose of this study is to evaluate efficacy and safety of osimertinib (tablet) in combination with Dato-DXd (i.v. infusion) compared with osimertinib (ta…

Non-small Cell Lung Cancer

Estimated

~$10 – $7,500

AstraZenecaNCT06350097

Phase 2

Randomized Phase II Study of Intermittent Versus Continuous Venetoclax Therapy With Acalabrutinib in Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Variants of This

This is a randomized Phase II study of intermittent versus continuous venetoclax therapy with Acalabrutinib in previously untreated Chronic Lymphocytic Leukemi…

Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaCLL Variant

Estimated

~$10 – $7,500

Zulfa OmerNCT07014917

BostonGene and Exigent Genomic INsight (BEGIN) Study: A Prospective Study of Comprehensive Molecular Testing in Advanced Cancer Patients in the Community Setting

The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the Bost…

Breast CancerNon-small Cell Lung CancerMelanoma+1 more

Estimated

~$10 – $1,125

BostonGeneNCT06272864

Phase 1

A Phase 1b, Two-Part Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer

A study of tolododekin alfa (also known as ANK-101) administered in combination with an anti-programmed cell death protein 1 (PD-1)/programmed cell death ligan…

Non Small Cell Lung Cancer

Estimated

~$10 – $8,750

Ankyra Therapeutics, IncNCT07027514

Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, …

Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more