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Parkinson's Progression Markers Initiative Online Study (PPMI Online)
Parkinson Progression Marker Initiative Online (PPMI Online) is an observational study collecting participant reported information from people with and without…
Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder
This project will test the hypotheses that people with 5-HT RBD have systemic alpha- synuclein pathology, prodromal DLB signs, and brainstem lesions in regions…
"SwallowFit," an Exercise Program and Randomized Clinical Trial Designed for US Service Members, Veterans, and Families Affected by Parkinson's Disease.
The goal of this clinical trial is to learn if a proactive swallow exercise will help to improve swallow fitness in patients with Parkinson's disease. The aim…
The Parkinson's Genetic Research Study (PaGeR)
The Parkinson's Genetic Research Study (PaGeR), headed by Dr. Cyrus Zabetian, is searching for genes that increase the risk of developing Parkinson's disease (…
Detection of Phosphorylated Alpha-Synuclein in Colonic Tissue Biopsy During Routine Colonoscopy
The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease…
Blood Flow Restriction for Optimizing Balance in Parkinson's Disease
This study is being done to understand how reducing blood flow (BRT) during balance-challenging strengthening exercises (instability resistance training, or IR…
Efgartigimod for Stiff Person Syndrome (ESPS)
The goal of this clinical trial is to examine the proportion of patients with stiff person syndrome with no worsening in stiffness and/or spasms while on efgar…
Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery
This study aims to 1) characterize skeletal muscle pH during/after tourniquet use and 2) investigate any relationship between intraoperative tourniquet use and…
Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension Patients
Investigators plan to recruit 50 PAH patients from UofL PAH Clinic, with various degrees of severity (25 intermediate risk patients and 20 high risk patients) …
Improving the Perinatal Mental Health of Veterans With Serious Mental Illness Through Peer Support
Veterans with serious mental illness (SMI) are at high risk of exacerbation of mental illness in pregnancy and postpartum, with consequences including poor pre…
Mastery Learning in Communication Skills to Improve Milestone Performance and Burnout
The goal of this study is to determine whether mastery learning in communication skills can improve skills in a simulated environment and have translational im…
rTMS as a Cognitive Rehabilitation Approach in Veterans With Parkinson's Disease
The purpose of this study is to examine safety, feasibility, and the behavioral and brain effects of a non-invasive treatment, repetitive transcranial magnetic…