The Spastic Paraplegia - Centers of Excellence Research Network (SP-CERN) is a collaborative research consortium dedicated to advancing the understanding, diag…

Hereditary Spastic ParaplegiaPrimary Lateral SclerosisSPG4+6 more

~Estimated

~$10 – $750

Boston Children's HospitalNCT06553976

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP)

The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biolog…

Hereditary Spastic ParaplegiaSPG47SPG50+8 more

~Estimated

~$10 – $750

Boston Children's HospitalNCT04712812

Phase 1

Safety and Efficacy of AAV9/AP4B1 For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47): A Phase 1/2 Single-Center, Open-Label Study of Stereotactic Intra-cisterna Magna Administration

Safety and Efficacy of AAV9/AP4B1 For Patients with AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47): A Phase 1/2 Single-Center, Open-Label Study of…

HSPHereditary Spastic ParaplegiaHereditary Spastic Paraparesis+10 more

~Estimated

~$10 – $8,750

BlackfinBio LtdNCT06948019