The purposes of this study are to 1) identify the genes responsible for certain immune disorders, 2) learn about the medical problems they cause, and 3) learn …

DOK 8STAT1GATA2+2 more

~Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT00001467

Phase 1

Safety and Efficacy of Upadacitinib in Treatment of JAK/STAT Pathway Disorders With Activating Mutations

This study focuses on a genetic condition that affects the Janus Kinase-Signal Transducer and Activator of Transcription (JAK-STAT) immune signaling pathway. A…

JAK1 GOFSTAT1 GOFSTAT3 GOF+2 more

~Estimated

~$10 – $7,500

Lisa SatterNCT07670156