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1,369 recruiting studies matching your filters

Phase I Study of Preoperative Therapy Imatinib Mesylate and Fampridine in KIT Mutant Gastrointestinal Stromal Tumor (GIST)

The goal of this clinical trial is to learn what dose of the drug fampridine can be given safely together with imatinib (Gleevec) in patients with gastrointest…

Gastrointestinal Stromal Tumors

Estimated

~$10 – $6,250

University of California, San DiegoNCT07171203

Forecasting Relapse Outcomes With AlloHeme-based Risk Detection in Post-Allo-HCT AML/MDS Patients (FORWARD): A Multicenter, Prospective Observational Cohort Study in US Transplant Centers

AlloHeme is a blood-based monitoring test developed by the CareDx laboratory that utilizes NGS technology coupled with a proprietary algorithm to predict the l…

AML (Acute Myelogenous Leukemia)MDS (Myelodysplastic Syndrome)CMML

Estimated

~$10 – $1,125

CareDxNCT07607327

Pharmacogenomics of Age-Specific, Asparaginase-Induced Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia

This pilot trial studies the impact of genetic information on developing liver damage caused by asparaginase in participants with newly diagnosed acute lymphob…

Acute Lymphoblastic Leukemia

Estimated

~$10 – $750

University of Southern CaliforniaNCT03568266

Phase 2

Hematopoietic Stem Cell Transplantation From Haploidentical Donors in Patients With Hematological Malignancies Using a Treosulfan-Based Preparative Regimen

This phase II trial studies how well a donor stem cell transplant, treosulfan, fludarabine, and total-body irradiation work in treating patients with blood can…

Acute LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+16 more

Estimated

~$10 – $6,250

Fred Hutchinson Cancer Center

Observational

Expanding Safe Spaces 4 Sexual Health, a Mobile Van HIV/STI Testing and Care Linkage Strategy, for MSM in Online Spaces

In an earlier study, the study team carried out an HIV/Sexually transmitted infection (STI) testing approach which found men who have sex with men (MSM) at-ris…

HIV Counseling and TestingHIV Risk BehaviorHIV Prevention

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT07133555

Phase 2

Phase II Study of the Hyper-CVAD Regimen in Sequential Combination With Blinatumomab With or Without Inotuzumab Ozogamicin as Frontline Therapy for Adults With B-Cell Lineage Acute Lymphocytic Leukemia

This phase II trial studies how well blinatumomab, inotuzumab ozogamicin, and combination chemotherapy work as frontline therapy in treating patients with B ac…

B Acute Lymphoblastic LeukemiaB Lymphoblastic Lymphoma

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT02877303

Biospecimen Collection and Donation to the AIDS and Cancer Specimen Resource (ACSR): A Companion Protocol to AMC Trials

This study collects blood and tissue samples for research of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS)-related cancers. Coll…

Anal CarcinomaHematopoietic and Lymphoid Cell NeoplasmHIV Infection+9 more

Estimated

~$10 – $1,125

AIDS Malignancy ConsortiumNCT05663502

Phase 2

A Phase II Study of Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) in Patients With Progressing Metastatic Neuroendocrine Carcinomas (NECs)

This phase IIa trial compares the safety and effect of temozolomide combined with survivin long peptide vaccine (SurVaxM) to temozolomide alone in patients wit…

Digestive System Neuroendocrine NeoplasmLung Neuroendocrine NeoplasmMalignant Solid Neoplasm+1 more

Estimated

~$10 – $7,500

Roswell Park Cancer InstituteNCT06202066

Phase 4

Flex Appeal: A Prospective Randomized Controlled Trial Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia (MUA)

The purpose of this study is to determine if changing the type of anesthesia improves the outcomes of manipulation and pain control after the procedure. The st…

Knee Stiffness After Total Knee Arthroplasty

Estimated

~$10 – $6,250

Duke UniversityNCT07348614

Observational

Evaluation of Innovative Placental Imaging Techniques in Fetal Growth Restriction

The goal of this proof-of-concept, case-control, clinical trial is to evaluate the efficacy of using two newer ultrasound technologies, quantitative ultrasound…

Fetal Growth Restriction (FGR)Placental InsufficiencyPreeclampsia+5 more

Estimated

~$10 – $6,250

Carilion ClinicNCT06861309

Phase 1

A Phase 1b, Open-label, Parallel Group, Multiple-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Oral Decitabine and Cedazuridine (ASTX727) in Cancer Patients With Moderate and Severe Hepatic Impairment

This is a Phase 1b, multicenter, open-label, pharmacokinetic (PK), and safety study of multiple oral doses of oral decitabine and cedazuridine (formerly known …

Acute Myeloid LeukemiaMyelodysplastic Syndromes

Estimated

~$10 – $8,750

Taiho Oncology, Inc.NCT04953910

Multi-centric Observational Study to Analyse the Diagnostic Molecular Features in the Clinical Setting of Kidney Allograft Biopsies

The current standard for biopsy-based diagnoses of dysfunction of kidney transplants is the Banff Classification which represents arbitrary international conse…

Validation Study of Molecular Diagnostic SystemDevelopment of Reporting System for Molecular DiagnosisIncorporate Molecular Diagnosis Into Diagnostic Standards

Estimated

~$10 – $750

University of AlbertaNCT01299168