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Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis
The purpose of this study is to characterize and assess the evolution of hearing impairment of patients with adulthood-onset bilateral sensorineural hearing lo…
Sensorineural Hearing Loss, Bilateral
SensorionNCT06354010
A Natural History Study in Individuals With Otoferlin Gene-mediated Hearing Loss
This is a retrospective and prospective longitudinal study in participants with Otoferlin Gene-Mediated Hearing Loss.
Sensorineural Hearing Loss, Bilateral
Akouos, Inc.NCT05572073
Phase 1
A Trial of AAVAnc80-hOTOF Gene Therapy in Individuals With Sensorineural Hearing Loss Due to Otoferlin Gene Mutations
Part A of this trial will evaluate the safety and tolerability of a single surgical administration procedure in one or both ear(s) with one of two dose levels …
Sensorineural Hearing Loss, Bilateral
Akouos, Inc.NCT05821959