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Observational
Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease
The goal of this interventional study is to learn about the impact of an intervention for health care providers that teaches individuation and perspective-taki…
Sickle Cell DiseaseSickle Cell Anemia in ChildrenSickle Cell Disease (SCD)+2 more
Connecticut Children's Medical CenterNCT07540767
Phase 4
Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease
This research is being conducted to see if using an injectable contraception, Depot Medroxyprogesterone Acetate (Depo-Provera), can reduce the pain experienced…
Sickle Cell Disease (SCD)Vaso-Occlusive Pain Episode in Sickle Cell Disease
University of PennsylvaniaNCT06665997
Sickle Cell Kidney (SCeK) Biorepository
Kidney disease is a major cause of illness and death in people with sickle cell disease and sickle cell trait. Despite these concerning facts, we do not (1) ha…
Sickle Cell TraitSickle Cell Disease (SCD)Chronic Kidney Disease
University of Texas Southwestern Medical CenterNCT07064174
Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease.
The WeDecide study is a large observational study comparing the long-term effects of matched related donor hematopoietic stem cell transplantation (MRD HCT) an…
Sickle Cell Disease (SCD)
University of RochesterNCT06941389