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3 recruiting studies matching your filters
Phase 1
RAdiation comBined With BIspecific T-Cell Engager in DLL3 Expressing Tumors (RABBIT) Study: A Phase I/II Study of AMG757 / Tarlatamab and Concurrent Radiation Therapy in Tumors With High Prevalence of DLL3
Phase I study to examine safety of the addition of concurrent tarlatamab with standard palliative and consolidative RT regimens , with a main cohort of N=20-24…
MelanomaMedullary Thyroid CancerSinonasal Undifferentiated Carcinoma+8 more
University of ArizonaNCT06814496
Phase 2
Perioperative Chemoimmunotherapy With Toripalimab for Sinonasal Cancer
The aim of this research study is to evaluate the effectiveness and safety of a combination of immunotherapy, using a drug called toripalimab, with chemotherap…
Sinonasal CancerParanasal Sinus NeoplasmsSquamous Cell Carcinoma+2 more
Glenn J. HannaNCT06940180
Phase 2
Phase II Study of Enasidenib in IDH2-mutated Malignant Sinonasal and Skull Base Tumors
Background: Cancers of the nasal cavity or skull base are rare. They often are not diagnosed until they are at an advanced stage, and they often spread to oth…
Metastatic ChondrosarcomaLocally Advanced ChondrosarcomaMetastatic Sinonasal Adenocarcinoma+7 more
National Cancer Institute (NCI)NCT06176989