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Phase 2
Internet-based Insomnia Intervention to Prevent Cognitive Decline in Older Adults With Mild Cognitive Impairment (SHUTi MIND)
This randomized controlled trial will evaluate the impact of an Internet-delivered cognitive behavioral therapy for insomnia (CBT-I) intervention on sleep and …
InsomniaCognitive DysfunctionMild Cognitive Impairment+6 more
University of VirginiaNCT05565833
Phase 3
A Multicenter, Double-blind, Randomized Study to Evaluate the Effects of Tasimelteon vs. Placebo in Participants With Delayed Sleep-Wake Phase Disorder (DSWPD)
This is a multicenter, double-blind, randomized study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon and matching placebo in ma…
Sleep Wake DisordersSleep Disorders, Circadian RhythmChronobiology Disorders
Vanda PharmaceuticalsNCT04652882
The SLEEPR Study: SLEep Effects on Post-stroke Rehabilitation
Sleep is critical for health and quality of life; however, little is known about the prevalence or impact of non obstructive sleep apnea (non-OSA) sleep disord…
StrokeSleep Wake DisordersRehabilitation+1 more
State University of New York - Upstate Medical UniversityNCT05012605
Observational
The Mind After Midnight: Mechanistic Examination of Nocturnal Wakefulness as a Suicide Risk Factor
This study examines whether wakefulness during the biological night (2:00-4:00 AM) is associated with increased negative mood, impaired decision-making, and su…
Suicidal IdeationCircadian Rhythm DisordersSleep Deprivation+1 more
University of ArizonaNCT07438912