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8 recruiting studies matching your filters

A Multicenter, Double-blind, Placebo-controlled, Randomized Withdrawal Study of Solriamfetol in Subjects With Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms

CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-control…

Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms

Estimated

~$10 – $8,750

Axsome Therapeutics, Inc.NCT07484217

Phase 3

A Multi-center, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of Solriamfetol in Excessive Sleepiness Associated With Shift Work Disorder

SUSTAIN (Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder) is a Phase 3, multi-center, randomized, double-blind,…

Excessive SleepinessShift-work Disorder

Estimated

~$10 – $8,750

Axsome Therapeutics, Inc.NCT06568367

Observational

A Randomized, Double-Blind, Controlled Trial of Bright Light Therapy on All-Cause Excessive Daytime Sleepiness in Prader-Willi Syndrome

This is a placebo controlled clinical trial to assess the utility of light therapy as a sufficient treatment for excessive daytime sleepiness in patients with …

Prader-Willi SyndromeExcessive Daytime SleepinessHyperphagia+3 more

Estimated

~$10 – $6,250

Maimonides Medical CenterNCT05939453

Observational

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population. OSA…

Sleep Apnea SyndromeObstructive Sleep ApneaCOPD+6 more

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT04179981

Phase 1

A Randomized, Double-blind, Sponsor-open, Placebo-controlled Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Ascending Doses of ORX142 in Healthy Adults, Single Doses of ORX142 in Healthy Older Adults, and a Single Dose Crossover, Proof-of-concept Study of ORX142 in Acutely Sleep-deprived Healthy Subjects

Characterize the safety, tolerability and pharmacokinetics of ORX142 following single and multiple doses.

Excessive Daytime Sleepiness

Estimated

~$10 – $8,750

Centessa Pharmaceuticals (UK) LimitedNCT07082829

Observational

Effect of Whole Food Plant-based Diet in Patients With Obstructive Sleep Apnea

This research aims to develop a better understanding and clinical knowledge of the effects of a plant based diet on severity and daytime sleepiness in Obstruct…

Obstructive Sleep ApneaDaytime Sleepiness

Estimated

~$10 – $6,250

Mayo ClinicNCT06395181

Observational

Evaluation of Perceived Outcomes With AGZ: A Randomized, Controlled, Consumer Perception Study

The study will be a prospective randomized, controlled clinical study. There will be interventional treatment for a total of 30 days. The subjects will complet…

SleepRelaxationStress+1 more

Estimated

~$10 – $7,500

Athletic Greens InternationalNCT07311434

Observational

Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness (STILL TIRED)

Obstructive sleep apnea (OSA) is a sleep disorder that is commonly treated using positive airway pressure, yet 50% of patients still experience residual sleepi…

Obstructive Sleep ApneaSleepiness

Estimated

~$10 – $7,500

NYU Langone HealthNCT06698809