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Radiofrequency Ablation/Bone Augmentation + Radiotherapy vs Radiotherapy Alone
This is a single-center, randomized controlled pilot study of radiofrequency ablation and bone augmentation (RFA/BA) plus radiotherapy (RT) vs. RT alone in pat…
Non-invasive Evaluation of Upper and Lower Body Function With Showmotion
It is very important to understand joint and body kinematics and muscles activity in clinical settings, which is relevant to identify issues related to the spi…
Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery
Having spine surgery and recovery is a vulnerable period when opioid naive patients may transition into long-term use of opioids, and when previously opioid to…
Comparing Multifidus Cervicis Plane Block Vs. Sham Block, In Reducing Postoperative Pain And Opioid Consumption In Patients Undergoing Elective Primary Posterior Cervical Spine Fusion Surgery
The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sha…
Dose-Escalated Spine SbRT (DESSRT) for Localized Metastasis to the Spinal Column
This study is being done to determine the feasibility and tolerability of a novel regimen of spine stereotactic radiosurgery (SSRS). SSRS delivers high doses o…
Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain, and the Role of Water
Significance to VA: There is a lack of prospective longitudinal studies investigating the relationship between risk factors to Veterans and development and pro…
Safety and Performance of the ThecaFlex DRx™ System Port and Catheter for Chronic Intrathecal Access, Cerebrospinal Fluid (CSF) Aspiration, and DElivery of Nusinersen in Spinal Muscular Atrophy (SMA) Patients Resistant to Lumbar PunctuRE Trial (PIERRE)
The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects…
Improving Surgical Outcomes With Early Physical Therapy After Anterior Cervical Discectomy and Fusion
The goal of this two-group randomized clinical trial is to examine the effects of early postoperative PT compared to delayed postoperative PT for improving out…
Congenital Muscle Disease Patient and Proxy Reported Outcome Study
The Congenital Muscle Disease Patient and Proxy Reported Outcome Study (CMDPROS) is a longitudinal 10 year study to identify and trend care parameters, adverse…
Spine Patient Optimal Radiosurgery Treatment for Symptomatic Metastatic Neoplasms (SPORTSMEN) Multicenter Randomized Phase II Clinical Trial
The purpose of this study is to compare three types of radiation therapy for cancer that has spread to the spine. The two types of radiation therapy used in th…
Personalized Spine Study Group (PSSG) Registry of Patients With Personalized Spine Rod Implantation
The primary objective of the study is a data collection initiative. The study will collect clinical and radiographic outcomes of patients implanted with patien…
The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion: A Randomized Control Trial
The purpose of this study is to evaluate if peri-operative zolpidem for posterior lumbar spinal fusion improves patient reported outcomes following surgery.