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Prospective Evaluation of Quality of Life and Utilities Following Surgical Treatment of Rectal Cancer
This study evaluates quality of life and utilities following surgical treatment of stage I-IV rectal cancer. This study may help researches learn more about qu…
Rectal AdenocarcinomaStage I Rectal Cancer AJCC v8Stage II Rectal Cancer AJCC v8+11 more
M.D. Anderson Cancer CenterNCT02107105
Phase 1
Organ Preservation for Patients With Locally Advanced Rectal Adenocarcinoma: Evaluating the Efficacy of Short Course Radiation Therapy Followed by FOLFOX or CapeOX
This phase I trial investigates how well short-course radiation therapy followed by combination chemotherapy works in treating patients with stage II-III recta…
Locally Advanced Rectal CarcinomaRectal AdenocarcinomaStage II Rectal Cancer AJCC v8+7 more
Jonsson Comprehensive Cancer CenterNCT04703101
Phase 1
Organ Preservation With Active Surveillance After Chemoradiation in Rectal Cancer (OPTION)
This pilot trial studies how well active surveillance and chemotherapy before surgery work in treating participants with stage II-III rectal cancer. Active sur…
Rectal AdenocarcinomaStage II Rectal Cancer AJCC v8Stage IIA Rectal Cancer AJCC v8+6 more
M.D. Anderson Cancer CenterNCT03594630
Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer
This study measures the levels of circulating tumor DNA (ctDNA) in patients with stage II-III rectal cancer before, during, and after treatment to find out if …
Rectal AdenocarcinomaStage II Rectal Cancer AJCC v8Stage IIA Rectal Cancer AJCC v8+6 more
OHSU Knight Cancer InstituteNCT05081024