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Observational

Cultural Tailoring and Pilot Testing of an Inpatient Yoga Therapy Program for Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation in India, Tanzania, and the United States

To develop and measure the effects of a culturally sensitive yoga program for inpatients

Hematopoietic Stem Cell TransplantationCancer

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT05681026

Observational

αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT) for Children and Young Adults With Hematologic Malignancies

This is a study utilizing the Magnetic-activated cell sorting (CliniMACS®) Alpha-Beta T-cell (αβT)/Cluster of Differentiation 19 (CD19), also called B lymphocy…

Hematopoietic Stem Cell TransplantationHematologic Malignancy

Estimated

~$10 – $6,250

Nationwide Children's HospitalNCT06082947

Phase 2

A Phase 2 Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Narsoplimab in Pediatric Patients (28 Days to ≤ 18 Years of Age.) With High-Risk Hematopoietic Stem Cell Transplant Thrombotic Microangiopathy

The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematop…

Thrombotic MicroangiopathiesHematopoietic Stem Cell Transplantation

Estimated

~$10 – $8,750

Omeros CorporationNCT05855083

Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

The primary purpose of the Research Sample Repository is to make blood samples available for research studies related to histocompatibility and hematopoietic c…

Autologous Stem Cell TransplantationAllogeneic Stem Cell TransplantationCellular Therapy+1 more

Estimated

~$10 – $1,125

Center for International Blood and Marrow Transplant ResearchNCT04920474

Observational

Remotely Monitored, Mobile Health-supported, High Intensity Interval Training Before Hematopoietic Stem Cell Transplantation (REMM-HIIT-HCT)

The goal of this clinical trial is to learn how a remotely monitored high-intensity interval training (REMM-HIIT) affects the cardiorespiratory fitness and phy…

Hematopoietic Stem Cell TransplantationCardiorespiratory Fitness

Estimated

~$10 – $6,250

University of Kansas Medical CenterNCT06953648

Phase 2

Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation (ADAPT)

This is a prospective, single-arm, phase II study. Patients will be treated with an allogeneic stem cell transplantation (AHSCT) using fludarabine, melphalan a…

Allogeneic Hematopoietic Stem Cell TransplantationAllogeneic Stem Cell TransplantationHematologic Malignancies

Estimated

~$10 – $6,250

University of California, IrvineNCT06028828

Protocol For A Research Database For Hematopoietic Stem Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

The primary purpose of the Research Database is to have a comprehensive source of observational data that can be used to study HSC transplantation and cellular…

Autologous Stem Cell TransplantationAllogeneic Stem Cell TransplantationSolid Tumors+4 more

Estimated

~$10 – $1,125

Center for International Blood and Marrow Transplant ResearchNCT01166009

Phase 1

Pilot Study of Haploidentical or Matched Donor Virus-Specific T-cells (Cytomegalovirus (CMV) or Adenovirus (AdV)) to Treat CMV or AdV Reactivation or Disease in Patients After Solid Organ or Hematopoietic Stem Cell Transplantation (HCT)

This trial studies the side effects and how well allogeneic cytomegalovirus-specific cytotoxic T lymphocytes (donor cytomegalovirus \[CMV\] specific cytotoxic …

Allogeneic Hematopoietic Stem Cell Transplantation RecipientCytomegalovirusDonor+2 more

Estimated

~$10 – $7,500

Sumithira VasuNCT03665675

Observational

A Randomized Controlled Trial of an Avatar-based Supportive Care Intervention for Patients Undergoing Outpatient Stem Cell Transplantation

The overall goal of this study is to assess the efficacy of the care.coach Avatar™ in improving anxiety and quality of life for patients undergoing outpatient …

Hematopoietic Stem Cell TransplantationCancer

Estimated

~$10 – $7,500

Victor WangNCT06564233

Phase 2

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) With Low-Dose Post-Transplant Cyclophosphamide for Prophylaxis of Graft-versus-Host Disease in Hematological Malignancies

This Phase 2, single-arm, open-label study aims to evaluate the safety and efficacy of low-dose (25 mg/kg) post-transplant cyclophosphamide (PTCy) for prophyla…

Graft-versus-Host Disease (GVHD)Hematologic MalignanciesAllogeneic Stem Cell Transplantation

Estimated

~$10 – $6,250

Milton S. Hershey Medical CenterNCT06926595

Phase 1

An Open-label, Non-randomized, Prospective Trial to Evaluate the Effect of Renal Function Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics in Patients With AML or MDS Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

This study aim is to assess, if treosulfan pharmacokinetics are influenced by declined renal function and by race/ethnicity of patients. The study also aims to…

Acute Myeloid Leukaemia (AML)Myelodysplastic Syndrome (MDS)Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Estimated

~$10 – $8,750

medac GmbHNCT05534620