This phase II trial studies the effect of P140K MGMT hematopoietic stem cells, O6-benzylguanine, temozolomide, and carmustine in treating participants with sup…

Glioblastoma MultiformeGlioblastoma Multiforme, AdultSupratentorial Glioblastoma+1 more

~Estimated

~$10 – $7,500

Leland MethenyNCT05052957

Phase 1

A Phase I Clinical Trial With a Window-of-Opportunity Component of Engineered NK Cells Containing Deleted TGF-ßR2 and NR3C1 in Recurrent Grade 4 Astrocytoma (Glioblastoma)

This phase I trial is to find out the best dose, possible benefits and/or side effects of engineered natural killer (NK) cells containing deleted TGF-betaR2 an…

Recurrent GliosarcomaRecurrent Supratentorial GlioblastomaSupratentorial Gliosarcoma

~Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT04991870