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4 recruiting studies matching your filters
Phase 1
A Multi-center, Phase 1/2a, First-in-human (FIH) Study Investigating the Safety, Tolerability, and Efficacy of AMT-260 in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy (MTLE) Administered Via Magnetic Resonance Imaging (MRI)-Guided Convection-enhanced Delivery (CED)
The main goals of this clinical study are to learn if AMT-260 is safe and tolerable and works to reduce the frequency of seizures in adults with unilateral mes…
Mesial Temporal Lobe Epilepsy
Estimated
~$10 – $8,750
UniQure Biopharma B.V.NCT06063850
Phase 3
A Study of Inhibitory Interneurons (NRTX-1001) in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE)
This clinical trial is designed to test whether a single image-guided intracerebral administration of inhibitory nerve cells, called interneurons (NRTX-1001), …
Mesial Temporal Lobe Epilepsy
Estimated
~$10 – $8,750
Neurona TherapeuticsNCT05135091
Observational
Overnight Temporal Interference Stimulation of Bilateral Hippocampi to Reduce Epileptogenic Biomarkers and Improve Sleep in Temporal Lobe Epilepsy
The goal of this clinical trial is to gauge whether overnight, non-invasive temporal interference (TI) stimulation aimed at the hippocampus can reduce abnormal…
Temporal Lobe Epilepsy (TLE)Drug Resistant EpilepsySleep
Estimated
~$10 – $6,250
Duke UniversityNCT07434986
Observational
Network Neuro-modulation for Mesial Temporal Lobe Epilepsy
In this study, participants will receive unilateral Deep Brain Stimulation (DBS) for treatment of epilepsy, with network-based stimulation targets specifically…
Mesial Temporal Lobe Epilepsy
Estimated
~$10 – $7,500
Nitin TandonNCT05608408