The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the max…

Central Nervous System NeoplasmsGlioblastomaGliosarcoma, Adult+20 more

~Estimated

~$10 – $8,750

Jazz PharmaceuticalsNCT04541082

Phase 1

Robust Armored Dual-Cytokine (IL-15/IL-21) GPC3-CAR T Cells for Atypical Teratoid Rhabdoid Tumors and Central Nervous System Rhabdoid Tumors (RADIANT)

This study is being conducted in patients with GPC3-positive brain tumors that have recurred or have not responded to standard therapy. Atypical teratoid rhabd…

Atypical Teratoid Rhabdoid TumorCentral Nervous System Rhabdoid Tumor

~Estimated

~$10 – $6,250

Baylor College of MedicineNCT07513194