Find your next paid study

National Institute of Allergy and Infectious Diseases (NIAID)NCT03937817

~$10 – $675

Sickle Cell DiseaseThalassemiaHemoglobinopathy

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling

Background: Sickle cell disease (SCD) is an inherited disorder of the blood. SCD causes red blood cells (RBCs) to die early. This can lead to a shortage of he…

National Heart, Lung, and Blood Institute (NHLBI)NCT06313398

~$10 – $5,625

Phase 3

A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study Evaluating the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Subjects With α- or β- Transfusion-Dependent Thalassemia

The primary objective of this study is to compare the effect of mitapivat versus placebo on transfusion burden in pediatric participants with α- or β-transfusi…

Transfusion-dependent Alpha-ThalassemiaTransfusion-dependent Beta-Thalassemia

Agios Pharmaceuticals, Inc.NCT07506863

~$10 – $8,750

Phase 3

A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study Evaluating the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Subjects With α- or β-Non-Transfusion-Dependent Thalassemia

The primary objective of this study is to compare the effect of mitapivat versus placebo on anemia in pediatric participants with alpha- or beta-non-transfusio…

Non-Transfusion-dependent Alpha-ThalassemiaNon-Transfusion-dependent Beta-Thalassemia

Agios Pharmaceuticals, Inc.NCT07517133

~$10 – $8,750

Phase 1/2 Study Evaluating the Safety and Efficacy of Gene Therapy Employing Lentiviral Vector ALS20-transduced Hematopoietic Progenitor Cells in Subjects With Transfusion-dependent-thalassemia

The main goal of this study is to find out if the blood disorder called transfusion-dependent beta thalassemia can be safely treated by modifying blood stem ce…

Beta-Thalassemia

Children's Hospital of PhiladelphiaNCT06364774

~$10 – $6,250

Phase 3

An Open-label, Multi-centre, Rollover Study to Characterise Long-term Safety and Efficacy of Etavopivat in Adults, Adolescents and Children Who Have Sickle Cell Disease or Thalassaemia and Have Completed a Treatment Period in an Etavopivat Study

Etavopivat is a new medicine under development for treating blood disorders like sickle cell disease and thalassaemia. Sickle cell disease and thalassaemia are…

Sickle Cell DiseaseThalassemia

Novo Nordisk A/SNCT06609226

Sickle Cell DiseaseBeta-thalassemia

Matched Related Donor Non-myeloablative Hematopoietic Cell Transplantation With Alemtuzumab, 400 cGy TBI, and Abatacept for Sickle Cell Disease and Beta-Thalassemia

This is a non-ablative (partial) stem cell transplant for patients with severe sickle cell disease or beta-thalassemia requiring red cell transfusions. The int…

National Heart, Lung, and Blood Institute (NHLBI)NCT07599176

~$10 – $5,625

International Prospective Registry of Patients With Alpha Thalassemia

This is an international prospective registry of patients with Alpha thalassemia to understand the natural history of the disease and the outcomes of fetal the…

Alpha-ThalassemiaAlpha Thalassemia MajorAlpha Thalassemia Minor

University of California, San FranciscoNCT04872179

~$10 – $675

Sickle Cell Disease (SCD)Sickle Cell Disease Vaso-occlusive CrisisSickle Cell Anemia Crisis+4 more

Buprenorphine for the Management of Pain in Children With Sickle Cell Disease

The goal of this clinical trial is to learn whether a single dose of buccal buprenorphine (BELBUCA) is safe when used in place and/or with full agonist opioids…

Natasha ArcherNCT07799571

Observational

A Multi-Center, Randomized, Controlled, Cross-Over Study to Evaluate the Effectiveness of Hypoxic Red Blood Cells Processed With the Hemanext ONE® System Versus Conventional Red Blood Cells in Patients With Transfusion Dependent Sickle Cell Anemia

The overall objective of this study is to evaluate the effectiveness and safety of transfusing hypoxic red blood cells manufactured with the Hemanext ONE syste…

Sickle Cell AnaemiaSickle Cell Anemia CrisisSickle Cell Anemia in Children+1 more

Hematologic DisorderBleeding DisorderConnective Tissue Disorder+10 more

HemanextNCT06743113

ATHN Transcends: A Natural History Cohort Study of the Safety, Effectiveness, and Practice of Treatment in People With Non-Neoplastic Hematologic Disorders

In parallel with the growth of ATHN's clinical studies, the number of new therapies for all blood disorders is increasing significantly. Some of the recently F…

American Thrombosis and Hemostasis NetworkNCT04398628

~$10 – $1,125

Sickle Cell AnemiaBeta-thalassemia MajorDiamond-blackfan Anemia

T-Cell Depleted, Alternative Donor Transplant in Pediatric and Adult Patients With Severe Sickle Cell Disease (SCD) and Other Transfusion-Dependent Anemias

The purpose of this study is to evaluate what effect, if any, mismatched unrelated volunteer donor and/or haploidentical related donor stem cell transplant may…