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Phase 2
A Phase 2 Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Narsoplimab in Pediatric Patients (28 Days to ≤ 18 Years of Age.) With High-Risk Hematopoietic Stem Cell Transplant Thrombotic Microangiopathy
The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematop…
Thrombotic MicroangiopathiesHematopoietic Stem Cell Transplantation
Omeros CorporationNCT05855083
TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients
Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy and pulmonary morbidity affects as many as 25% of children receiving transplant. Ea…
Hematopoietic Stem Cell Transplant (HSCT)Diffuse Alveolar HemorrhageThrombotic Microangiopathies+2 more
Children's Hospital Medical Center, CincinnatiNCT04098445