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8 recruiting studies matching your filters

A Phase 4, Single-Arm, Open-Label Trial to Evaluate the Safety and Efficacy of Veligrotug in Participants With Thyroid Eye Disease (TED) Who Previously Responded to Teprotumumab

This is a clinical trial to evaluate the safety and efficacy of veligrotug (LUMVOA™) in participants with moderate to severe TED who previously received and re…

Thyroid Eye Disease

Estimated

~$10 – $8,750

Viridian Therapeutics, Inc.NCT07832136

Phase 1

An Adaptive Phase 1/2 MulticenteR Study Evaluating the Safety, Tolerability, Pharmacokinetics and EfficaCy of VV-14305 Delivered Via PeribuLbAr Injection in Patients With Moderate to Severe Thyroid Eye Disease (the RECLAIM Study)

The goal of this study is to evaluate the safety, tolerability, and efficacy of KRIYA-586 (VV-14305) in treating thyroid eye disease (TED).

Thyroid Eye Disease (TED)

Estimated

~$10 – $8,750

Kriya Therapeutics, Inc.NCT07404111

Phase 3

A Phase 3, Randomized, Double-mask, Placebo-controlled Study With Open-label Extension to Evaluate the Efficacy and Safety of Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)

The goal of this clinical trial is to evaluate the efficacy, safety, and tolerability of linsitinib in participants with moderate to severe Thyroid Eye Disease…

Thyroid Eye Disease, TEDGraves Orbitopathy

Estimated

~$10 – $8,750

Sling Therapeutics, Inc.NCT07753603

Phase 2

An Open-label, Rollover Study for Participants With Thyroid Eye Disease Previously Enrolled in Amgen-sponsored AMG 732 Studies and Are Primary Proptosis Non-responders or Who Relapsed During the Safety Follow-up

The main objective of this trial is to assess the efficacy of AMG 732 in participants with thyroid eye disease (TED) who are defined as primary nonresponders o…

Prospective Observational Study of Smartphone-Based Self-Monitoring Using an Artificial Intelligence Solution During Non-Surgical Treatment for Thyroid Eye Disease

This prospective observational study evaluates the feasibility and clinical utility of a smartphone-based artificial intelligence (AI) self-monitoring system i…

Thyroid Eye Disease (TED)Graves OphthalmopathyThyroid Associated Ophthalmopathies

Estimated

~$10 – $1,050

THYROSCOPE INC.NCT07623993

Prospective Multicenter Observational Study for Clinical Validation of AI-Based Quantitative Eye Movement Analysis Using Smartphone-Recorded 9-Gaze Videos

This prospective, multicenter, multinational observational study evaluates the clinical validity of an AI-based quantitative eye movement analysis system (Glan…

Ocular Motility DisordersStrabismusExtraocular Muscle Dysfunction+1 more

Estimated

~$10 – $1,050

THYROSCOPE INC.NCT07623837

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

This protocol studies the clinical outcome of patients with active thyroid disease with visually significant signs and symptoms of proptosis, pain, diplopiam l…

Thyroid Eye DiseaseGraves OphthalmopathyGraves Disease

Estimated

~$10 – $750

Walter Reed National Military Medical CenterNCT06275373

Phase 2

A Multicenter, Extension Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled i…

Thyroid Eye DiseaseGraves OrbitopathyEndocrine System Diseases+9 more

Estimated

~$10 – $8,750

Sling Therapeutics, Inc.NCT06112340