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136 recruiting studies matching your filters

MRI of Epicardial Adipose Tissue Composition: Development of Methods and Application to Heart Failure With Preserved Ejection Fraction

This study seeks to develop improved cardiac MRI (CMR) methods to quantify epicardial adipose tissue (EAT) composition and to demonstrate the advantages of EAT…

Heart Failure Preserved Ejection FractionEpicardial Adipose Tissue

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of VirginiaNCT07178145

Phase 1

Application of Contrast-enhanced Ultrasound in Monitoring Soft Tissue Sarcoma Response to Neoadjuvant Radiotherapy

This pilot study will evaluate the feasibility of applying CEUS as imaging guidance for planning RT and predicting RT response. The investigators will determin…

Soft Tissue Sarcoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Thomas Jefferson UniversityNCT07436364

Characterization of the Genomic Risk Underlying Retroperitoneal Liposarcoma

The protocol intends to explore the biology which may underlie recurrences of retroperitoneal liposarcoma. Surgery remains the only curative intent interventio…

Retroperitoneal LiposarcomaSoft Tissue Sarcoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Fox Chase Cancer CenterNCT06436846

Phase 1

A First-in-human, Phase 1/2, Multicenter, Open-label, Dose Escalation and Expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of ADCE-D01, a Humanized Anti-human uPARAP Antibody Linked to a Topoisomerase I Inhibitor, in Patients With Metastatic and/or Unresectable Soft Tissue Sarcoma

The goal of this clinical trial is to learn about the safety, tolerability and efficacy of ADCE-D01.

Metastatic Soft Tissue SarcomaUnresectable Soft Tissue Sarcoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Adcendo ApSNCT06797999

Phase 3

Phase III Randomized Study Testing Non-Inferiority of Short-Course Ultra-Hypofractionated Radiation (UHRT-5) Versus Standard Fractionation (RT-25) for Stage II-IIIB, Extremity, Resectable Soft Tissue Sarcoma

This clinical trial compares the effect of short-course ultrahypofractionated radiation therapy over 5 days (UHRT-5) to standard-course radiation therapy over …

Recurrent Soft Tissue Sarcoma of the Trunk and ExtremitiesResectable Soft Tissue Sarcoma of the Trunk and ExtremitiesSoft Tissue Sarcoma of the Trunk and Extremities+2 more

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Phase 2

An Open Label Evaluation of Intralesional Injection of Sodium Thiosulfate in the Treatment of Cutaneous or Tendon Calcinosis in Connective Tissue Disease

The specific objective of this study is to perform a small, open-label study to assess the safety and efficacy of intralesional, subcutaneous injection of STS …

Systemic Sclerosis (SSc)DermatomyositisMixed Connective Tissue Disease (MCTD)+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Robyn T. Domsic, MD, MPHNCT06672822

Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study

This study generates information on the feasibility and acceptability of a 3-month ecological momentary assessment (EMA) protocol to assess chronic pain and op…

SarcomaChildhood Sarcoma of Soft Tissue

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Roswell Park Cancer InstituteNCT07402577

Phase 1

A Randomized Phase I/II Study of Talazoparib or Temozolomide in Combination With Onivyde in Children With Recurrent Solid Malignancies and Ewing Sarcoma

The phase I portion of this study is designed for children or adolescents and young adults (AYA) with a diagnosis of a solid tumor that has recurred (come back…

Recurrent Solid TumorRecurrent Ewing SarcomaRecurrent Hepatoblastoma+19 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Phase 1

Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

Checkpoint inhibitor therapy represents a significant advance in cancer care. The interaction between PD-1 and PD-L1 induces immune tolerance, and the inhibiti…

Bile Duct CancerGall Bladder CancerBreast Cancer+6 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of FloridaNCT05000294

Observational

The Effect of Enhanced Behavioral Healthcare on Self-Reported Depression, Anxiety, and Health-Related Quality of Life Among Patients With Musculoskeletal Sarcoma Undergoing Surgery: A Randomized Pilot Study

The purpose of this study is to investigate the feasibility of early access to mental healthcare during sarcoma treatment as well as to assess the association …

SarcomaBone SarcomaSoft Tissue Sarcoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT06129903

Observational

A Randomized Controlled Clinical Trial to Assess Soft Tissue Quantity and Quality Following the Use of Augmented Gingival Matrix Compared to Free Gingival Graft Around Implants-A 12-month Follow-up Study

This is a 12-month, randomized, examiner-blinded, controlled, two-arm, parallel-group, single-site clinical trial comparing a biocompatible tissue graft (Augme…

Keratinized Tissue Augmentation Around Dental Implants

Estimated

~$10 – $1,125

Actual pay is set by the research site.

The Forsyth InstituteNCT07863882

Phase 2

SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma

The goal of this clinical research study is to look at the effectiveness of giving a combination of chemotherapy, immunotherapy, radiation therapy, and surgery…

Soft Tissue Sarcoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT07049848