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Observational
A Randomized Controlled Trial Comparing Transcriptomic Profile Changes Following Carbon Dioxide (CO2) Laser Wedge Resection Versus Radial Incision for Benign Tracheal Stenosis
Some people develop a narrowing of their windpipe (trachea), called benign tracheal stenosis, which can make it hard to breathe. Doctors often treat this by us…
Tracheal Stenosis
University of Maryland, BaltimoreNCT07463742
Observational
A Randomized, Controlled, Multi-Center, Prospective Trial of Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Airway Stenosis (OXYGEN-RCT Trial)
The OXYGEN-RCT trial is a randomized, controlled, double blinded, prospective, multi-center trial to demonstrate the safety and efficacy in adult benign centra…
Adult Subjects With Symptomatic Benign Airway ObstructionAdult Benign Central Airway StenosisAdult Tracheobronchial Stenosis+3 more
Airiver Medical, Inc.NCT07191860
RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis
Benign tracheal stenosis is a rare but potentially life-threatening condition, typically resulting from fibroinflammatory scarring. It can be secondary to iatr…
Tracheal StenosisSubglottic Stenosis
University of Maryland, BaltimoreNCT07258784
Voice Quality Analysis of Patients With Laryngotracheal Stenosis
The investigators previously demonstrated that voice changes are common in patients with Laryngotracheal Stenosis (LTS), and patients typically report an impro…
Idiopathic Subglottic Tracheal Stenosis
Johns Hopkins UniversityNCT06161077