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Phase 3, Multicenter, Randomized, Subject and Evaluator Blinded, Controlled Study Evaluating the Safety and Efficacy of NTX-001 Compared to Standard of Care (Neurorrhaphy) in the Treatment of Upper Extremity Transected Nerves Requiring Surgical Repair.
NTX-001 is a single use surgical product intended for use in conjunction with standard suture neurorrhaphy of severed nerves in patients between 18 and 80.
A Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period to Evaluate the Efficacy and Safety of AGN-151607-DP (USAN: gemibotulinumtoxinA) for the Treatment of Upper Limb Essential Tremor in Adults
Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as…
Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain (VANISH)
The goal of this Registry is to see how the device is used when freezing nerves during an amputation procedure.
Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses
The purpose of this study is to characterize proprioceptive sensations in the missing limb of upper limb amputees using nerve stimulation, and to develop advan…
The Impact of Vagus Nerve Stimulation Paired With Rehabilitation on Lower Limb and Gait Functions After Ischemic Stroke
This is a prospective, double-blinded, randomized controlled study to evaluate the impact of Vagus Nerve Stimulation (VNS) therapy on lower limb function.
Regulatory Clearance of the Glide Control Strategy for Upper Limb Prostheses
The investigators will test the following hypothesis: Use of Glide results in improved functional performance, satisfaction, and usage metrics as compared to u…
Evaluating Adaptive Rock Climbing on Children With Upper Limb Differences
The goal of this clinical trial is to assess changes in functional and psychosocial outcomes following a 12-week adaptive rock-climbing program for children wi…
Neuromusculoskeletal Interface for Bionic Arms: A Randomized Crossover Study
The overall objective of this proposal is to perform a first-in-human home trial of the Electronic Osseoanchored Prostheses for the Rehabilitation of Amputees …
Regulatory Clearance of a Rehabilitation System for Individuals With Upper Limb Loss
The investigators propose to evaluate the efficacy of MyoTrain in a prospective clinical study involving 16 individuals with trans-radial upper-limb loss over …
Patient-specific Requirements and Experiences of Upper Limb Prosthetic Technology
The goal is to understand the critical factors associated with outcome acceptance following upper limb loss. The investigators aim to develop a unified theoret…
Determining the Long-Term Stability of the Glide Control Strategy for Upper Limb Prostheses
This research is intended to test whether the prescription of the Glide prosthesis control system reduces the burden of use for both patients and their clinica…
Promoting Healing of Injured Nerves With Electrical Stimulation Therapy
This study is evaluating a new therapeutic use of electrical stimulation to promote nerve healing and improve functional recovery following surgical interventi…