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21 recruiting studies matching your filters

A Randomized Trial Comparing Intravesical Gemcitabine to Continuous Bladder Irrigation With Sterile Water to Prevent Bladder Cancer Implantation in Patients Undergoing Excision of Upper Tract Urothelial Carcinoma

There is a high rate of intravesical (bladder) recurrence following extirpative surgery for upper tract urothelial carcinoma. There is no single established st…

Urothelial Cancer of Renal PelvisUrothelial Carcinoma Ureter

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT04865939

A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies

Background: Tumors in the genitourinary tracts can occur in the kidney, bladder, prostate, and testicles and can have common and rare histologies. Some cancer…

Urothelial CancerBladder CancerGenitourinary Cancer+2 more

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT04923178

Phase 2

IZABRIGHT-Bladder01: A Randomized, Open-label, Phase 2/3 Trial of Izalontamab Brengitecan Versus Platinum-based Chemotherapy for Metastatic Urothelial Cancer in Participants With Disease Progression on or After an Immunotherapy-based Treatment

A Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer with Disease Progression on or After Immunotherapy

Urothelial Cancer

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07106762

Specimen Collection for Validation of UroAmp: A Next Generation Sequencing Platform for Detection and Surveillance of Bladder Cancer

This is a prospective, multicenter observational study designed to collect urine and tumor biospecimens and associated clinical data from patients undergoing e…

Bladder CancerUrothelial Carcinoma (UC)Hematuria+1 more

Estimated

~$10 – $1,050

Convergent Genomics, Inc.NCT07673016

Phase 2

A Phase II Clinical Trial of Anti-PD-1 mAb Therapy Alone or With Metabolic Modulators to Reverse Tumor Hypoxia and Immune Dysfunction in Solid Tumor Malignancies

Patients with histologically or cytologically confirmed advanced melanoma, renal cell carcinoma, NSCLC, HCC (Child Pugh Class A only), MSI-High solid tumors, U…

MelanomaNSCLCHepatocellular Carcinoma+5 more

Estimated

~$10 – $7,500

Dan ZandbergNCT04114136

Phase 1

A Phase 1, Open-Label Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of GB-4362 Administered With Enfortumab Vedotin and Pembrolizumab in Participants With Advanced Urothelial Cancer

The purpose of this study is to evaluate the safety and tolerability of an investigational drug called GB-4362 when it is given together with enfortumab vedoti…

Advanced Urothelial CancerMetastatic Urothelial Carcinoma

Estimated

~$10 – $7,500

Generate BiomedicinesNCT07484022

Phase 1

Combinations of Sacituzumab Govitecan Plus Enfortumab Vedotin and Pembrolizumab for Metastatic Urothelial Carcinoma: the Double Antibody Drug Conjugate (DAD) and Double Antibody Drug Conjugate With Immunotherapy (DAD-IO) Phase I/II Trial

Phase I of this research study will assess what doses of Sacituzumab Govitecan and Enfortumab Vedotin can be safely combined in the treatment of metastatic uro…

Urothelial CancerMetastatic Urothelial CarcinomaMetastatic Urothelial Carcinoma of the Renal Pelvis and Ureter+1 more

Estimated

~$10 – $7,500

Dana-Farber Cancer InstituteNCT04724018

Phase 2

A Phase II Trial of SeqUential GeMcitabine and MITomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma (SUMMIT)

This Phase II clinical trial, titled "A Phase II Trial of Sequential Gemcitabine and Mitomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial…

Urinary Bladder CancerUpper Tract Urothelial CancerUrothelial Cancer

Estimated

~$10 – $6,250

Rutgers, The State University of New JerseyNCT06822010

Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer of the Bladder and Kidney

The purpose of this study is to determine if analysis of DNA and protein material found in urine will be useful in the detection of urothelial cancer of the bl…

Urothelial CancerCancerBladder Neoplasms+1 more

Estimated

~$10 – $750

Lahey ClinicNCT00872495