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Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients
The goal of this observational study is to investigate how bacterial populations from the intestine and mouth of patients change during the hospitalization per…
Antimicrobial Drug ResistanceAntibiotic Resistant InfectionClostridium Difficile+5 more
The Methodist Hospital Research InstituteNCT06258551
Phase 2
Enteral Vancomycin as Primary Prophylaxis Against Clostridioides Difficile Infection in Critically Ill Patients
The goal of this clinical trial is to determine if oral vancomycin can prevent C.diff infection in adults who are critically ill and are at high risk of C.diff…
Clostridium Difficile InfectionVancomycin Resistant Enterococci Infection
Riverside University Health System Medical CenterNCT07221370
Observational
Implementing Vancomycin Reducing Practices (VRP) in Preterm Infants
This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). …
Antibiotic StewardshipNeonatal Sepsis, Late-OnsetVancomycin
Children's Hospital of PhiladelphiaNCT06772675
Phase 2
Primary Prophylaxis of Clostridioides Difficile Infection With Oral Vancomycin in Patients Treated With Systemic Antibiotic Therapy in a Community Hospital
The purpose of this study is to evaluate the ability of oral vancomycin in preventing Clostridioides difficile infection (CDI) in patients that are simultaneou…
Clostridioides DifficileVancomycin Resistance Enterococcus Faecium
University of Maryland, BaltimoreNCT07221708