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Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults: A Randomized Control Trial

The purpose of this research is to see if ketamine is effective and safe in treating children and young adults with sickle cell disease experiencing sickle cel…

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more

Estimated

~$10 – $7,500

Mohsen SaidinejadNCT07369024

Phase 4

Evaluation of a Standardized Low-Dose Bolus Ketamine Pathway for Management of Pediatric Sickle Cell Patients Presenting to the Emergency Department With Pain

The goal of this study is to learn if Ketamine works more efficiently, as compared to Opioids, for Sickle Cell Pain The main questions it aims to answer are: …

Vaso-Occlusive Pain Episode in Sickle Cell DiseaseSickle Cell Disease (SCD)

Estimated

~$10 – $6,250

University of Mississippi Medical CenterNCT07682662

Phase 4

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

This research is being conducted to see if using an injectable contraception, Depot Medroxyprogesterone Acetate (Depo-Provera), can reduce the pain experienced…

Sickle Cell Disease (SCD)Vaso-Occlusive Pain Episode in Sickle Cell Disease

Estimated

~$10 – $6,250

University of PennsylvaniaNCT06665997

Observational

Pilot Study to Investigate the Use of Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

This study aims to evaluate the use of virtual reality as an adjunct to standard care for patients with sickle cell disease experiencing vaso-occlusive crises.

Sickle Cell DiseaseVaso-occlusive Pain Episode in Sickle Cell DiseaseAcute Pain

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT06184126