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6 recruiting studies matching your filters

A 2-Part, Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study to Assess Efficacy and Safety of REGN7508, a Monoclonal Antibody Against Factor XI, for the Treatment and Secondary Prevention of Venous Thromboembolism in Participants With Solid and Hematologic Cancers (ROXI-CAT-II)

This study is researching an experimental drug called REGN7508 (called "study drug") and will consist of 2 parts: Part 1 and Part 2. The study is focused on pa…

Venous Thromboembolism (VTE)

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07493304

Phase 3

A Phase 3, Multicenter, Randomized, Open-Label, Study to Evaluate REGN7508, A Factor XI Monoclonal Antibody, Versus Apixaban and Enoxaparin for Prophylaxis of Venous Thromboembolism After Elective Total Knee Arthroplasty (ROXI-APEX)

This study is researching an experimental drug called REGN7508 (called "study drug"). The study is focused on adults undergoing elective, unilateral (one side)…

Venous Thromboembolism (VTE)

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07015905

Phase 3

A Phase 3, Multicenter, Double-Blinded, Randomized Study to Evaluate REGN7508, a Factor XI Monoclonal Antibody, Versus Acetylsalicylic Acid for Prophylaxis of Symptomatic Venous Thromboembolism After Elective Total Knee Arthroplasty (ROXI-ASPEN)

This study is researching an experimental drug called REGN7508 (called "study drug") and how it compares against another treatment called Acetylsalicylic Acid …

Symptomatic Venous Thromboembolism (VTE)

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07213778

Phase 4

Extended Prophylactic Anticoagulation Following Spinal Surgery for Metastatic Disease

People who have surgery on their spine to treat cancer that has spread (metastatic disease) have a high chance of developing dangerous blood clots in the legs …

Venous Thromboembolism (VTE)Deep Vein Thrombosis (DVT)Pulmonary Embolism (PE)+1 more

Estimated

~$10 – $7,500

James BayleyNCT07713875

Phase 3

Collaborative Risk-stratified Investigation in Thrombosis-prone Inpatients With Critical Illness: Anticoagulation With LMWH in Teens for ThromboProphylaxis (CRITICAL-Teens-TP)

Critically ill adolescents are at greatest risk for developing hospital-acquired venous thromboembolism. To date, no phase 3 randomized controlled trials have …

Venous Thromboembolism (VTE)

Estimated

~$10 – $6,250

Johns Hopkins All Children's HospitalNCT06628778

DUH Innovation Units

This quality improvement initiative aims to evaluate the implementation, utilization, and impact of virtual care technologies and workflows being implemented a…

Falls InjuryReadmission RatesCLABSI - Central Line Associated Bloodstream Infection+6 more

Estimated

~$10 – $750

Duke UniversityNCT07406074