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4-aminopyridine for Skin Wound Healing
Many patients suffer from chronic non-healing wounds as well as acute wounds. There is a need to develop treatments to accelerate and improve healing of chroni…
Impact of A Postoperative Meal Delivery Program on Malnutrition in Orthopaedic Trauma Patients
The purpose of this study is to examine the impact of a medically tailored post-operative meal delivery program on surgical outcomes and metabolic lab markers …
A Randomized Controlled Trial of Abdominal Ultrasound (FAST) in Children With Blunt Torso Trauma
Bleeding from intra-abdominal injuries is a leading cause of traumatic deaths in children. Abdominal CT is the reference standard test for diagnosing intra-abd…
APPRAISE 2.0: Live Trial of the APPRAISE Trauma Decision Support System
This is a pilot evaluation of the APPRAISE trauma decision-support software system ("the System"). The specific objections are as follows: 1. Evaluate the rob…
Blood Flow Restriction Training After Patellar INStability (BRAINS Trial)
This research study is designed to allow health care professionals and researchers to answer many questions about whether a new type of physical therapy called…
Development and Validation of a Novel Machine-learning Algorithm to Assist in Handheld Vascular Diagnostics
The use of handheld arterial 'stethoscopes' (continuous wave Doppler devices) are ubiquitous in clinical practice. However, most users have received no formal …
Human Upper Extremity Allotransplantation
Background: Millions of people each year sustain injuries, have tumors surgically removed, or are born with defects that require complex reconstructive surgeri…
SC2i-WounDx-001-WounDx™ Pilot Trial: Proof of Concept Feasibility for the Clinical Operations of WounDx™ in Aiding Clinicians Identify Wounds That Are Ready For Surgical Closure
The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital. The WounDx device is experi…
Human Craniomaxillofacial Allotransplantation
Background: The human face is critically important for breathing, eating, seeing, and speaking/ communicating, but its most important job may be to look like a…
Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness
This unblinded Phase II clinical trial will test the effects of individualized acupuncture treatments offered in extant acupuncture practices in the community;…
4-Aminopyridine to Treat Skin Burns
Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured sk…
Feasibility Study for Fibroblast Autologous Skin Grafts: Biopsy of Skin Fibroblasts, Expansion in Cell Therapy Core, Topical Injection of Fibroblasts, and Subsequent Removal of Graft for Laboratory Studies.
This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal…