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Phase 1
EXPAND: A Prospective Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With End-stage Renal Disease (ESRD)
The purpose of this study is to evaluate the safety and efficacy of the 10 GE Xenokidney in patients with ESRD who are either not eligible for conventional all…
ESRD (End-Stage Renal Disease)Kidney TransplantationXenotransplantation
United TherapeuticsNCT06878560
Phase 1
EXTEND: A Prospective Study to Evaluate the Safety and Efficacy of GGTA1 KO Thymokidney XenoTransplantation in Patients With End-stage Renal Disease (ESRD)
The purpose of this study is to evaluate the safety and efficacy of the GGTA1 KO Thymokidney in patients with end-stage renal disease (ESRD) who are either not…
ESRD (End-Stage Renal Disease)Kidney TransplantationXenotransplantation
United TherapeuticsNCT07224763
Phase 1
A Phase I/IIa, Single Site, Open-Label, Ascending Dose Study to Evaluate the Safety and Efficacy of OPF-310 [Encapsulated Porcine Islet Cells for Xenotransplantation] in Subjects With Type 1 Diabetes Mellitus
This study is First In Human study for Encapsulated Porcine Islet Cells for Xenotransplantation (OPF-310). The purpose of this study to assess the safety, tole…
Diabetes Mellitus, Type 1HypoglycemiaIslet Cell Transplantation+14 more
Otsuka Pharmaceutical Factory, Inc.NCT06575426