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Biomarker-Guided Antidepressant Selection for Treatment-Resistant Depression
Depression is one of the leading causes of disability worldwide. Common treatments like antidepressant medications and talk therapy work well for some people, …
Top-Down Attentional Control of Visual-Processing
Background: \- Previous studies have shown that people with certain types of brain damage may have particular problems paying attention and processing things …
Neuromodulation of Mood Switch Circuitry in Bipolar Disorder
This study is exploring a new approach to treating depression in people with bipolar disorder (BD). Investigators are testing whether a non-invasive form of br…
A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty
Despite the clear importance of adolescence in the emergence of a number of disease states and processes, there is surprisingly little known about how the endo…
TMS Investigations of the Human Visual System
Background: -The brain has two systems for recognizing objects. One system recognizes what an object is, and the other system recognizes where the object is l…
Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI Contrast
The purpose of this investigation is to develop improved magnetic resonance imaging (MRI) techniques and hardware for studying brain function. MRI is a diagnos…
The Effect of Light Intervention on Recovery in Individuals With Opioid Use Disorder (OUD)
Opioid use disorder (OUD) is a chronic relapsing disorder and is well-known for its high-risk rate of overdoses and death. In OUD, sleep and circadian disrupti…