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27,270 recruiting studies available now

A Phase 1, First-in-Human Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Participants With Prostate Cancer

There are many treatment options for men with various stages of prostate cancer. Some treatments work well for a while but can cause medical problems in some m…

Hormone-refractory Prostate Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Astellas Pharma Global Development, Inc.NCT05997615

Observational

Early Feasibility Study of the DUO Transcatheter Tricuspid Coaptation Valve System in Patients With Tricuspid Regurgitation

The study is an early feasibility study to measure individual patient clinical outcomes and effectiveness, evaluate the safety and function of the DUO Transcat…

Tricuspid RegurgitationTricuspid Valve InsufficiencyTricuspid Valve Disease+1 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

CroiValve LimitedNCT05913908

Phase 1

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

Background: Neuroblastoma is a type of cancer that causes tumors in nerves. It affects mainly infants and toddlers, and it causes about 15 percent of cancer-r…

Neuroblastoma

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06995872

Phase 2

A Double Blind, Placebo-controlled Trial of LAM-001 for Treatment of Sarcoidosis Associated Pulmonary Hypertension (SAPH)

A Phase 2, Randomized, Double-Blind, Multi-Dose, Placebo-Controlled Study to Evaluate the Efficacy and Safety of LAM-001 (Inhaled Sirolimus) in Adults with Sar…

Sarcoidosis Associated Pulmonary Hypertension

Estimated

~$75 – $2,800

Actual pay is set by the research site.

IRulya Therapeutics Inc.NCT07886554

Observational

REACT Biomarker and Extended-Measures Study: Hair Steroids, Psychosocial Moderators, and Momentary Reactive Behavior in College Students

This study looks at the moments when college students feel a strong emotional swing, and how those moments relate to reacting online when upset, drinking alcoh…

Emotional RegulationAlcohol Drinking in CollegeEmotional Eating+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of FloridaNCT07782398

Observational

ARISE: Achieving Routine Intervention and Screening for Emotional Health: Randomized Controlled Trial

The purpose of this project is to evaluate the effectiveness of diabetes distress screening and intervention on patients with type 2 diabetes mellitus (T2DM).

Type 2 Diabetes Mellitus (T2DM)Diabetes Distress

Estimated

~$10 – $750

Actual pay is set by the research site.

University of ChicagoNCT06887049

Phase 1

A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma.

This is a Phase 1, open-label, dose-escalation study of CBX-663 in participants with R/R AML, MDS or CMML (Cohort A), advanced solid tumors (Cohort B), or recu…

Advanced Solid TumorsRecurrent or Progressive GlioblastomaRelapse or Refractory Myeloid Malignancies

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Crossbow Therapeutics, Inc.NCT07779798

Observational

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure (BENEFIT-HF)

The purpose of BENEFIT-HF is to demonstrate the safety and effectiveness of Baroreflex Activation Therapy (BAT) with the Barostim System in participants with h…

Heart FailureHeart Failure NYHA Class IIHeart Failure NYHA Class III

Estimated

~$10 – $1,050

Actual pay is set by the research site.

CVRx, Inc.NCT07232030

Phase 2

A Multicenter, Open-label, Phase IIb Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC (Non-resistant Uncommon EGFR Mutations Only, Including L861Q, G719X, and/or S768I)

This is a Phase 2b, multicenter, open-label study to evaluate the safety and efficacy of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC (Non…

Non-small Cell Lung Cancer

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Teligene USNCT05168566

Phase 1

A Phase I Study to Assess the Safety and Antitumor Activity of Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Background: Small cell lung cancer (SCLC) is the deadliest form of lung cancer. Extrapulmonary neuroendocrine cancer (EPNEC) is a similar type of cancer that …

Recurrent Small Cell Lung CancerExtensive-Stage Small Cell Lung CancerSmall Cell Lung Cancer+6 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)

Phase 2

A Proof-of-Concept Open-Label Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of CSTI-500 in Participants With Prader-Willi Syndrome

This is a proof-of-concept, open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CSTI-500 in participants …

Prader-Willi Syndrome

Estimated

~$75 – $2,800

Actual pay is set by the research site.

ConSynance TherapeuticsNCT07348601

Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vulvar Lesions: A Pilot Study

This purpose of this study is to assess the feasibility of using the DermaSensor™ device on vulvar skin.

Vulvar Intraepithelial Neoplasia, HPV-IndependentVulvar Squamous Cell CarcinomaVulvar Squamous Intraepithelial Lesion, HPV-Associated

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07886203