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27,292 recruiting studies available now

Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer (MAPPER)

This is an exploratory phase II interventional study that initiates standard-of-care anti-estrogen treatment preoperatively for 4-12 weeks (+/- 2 weeks).

Breast Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Medical College of WisconsinNCT06361940

Observational

Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing

This 2x2 randomized crossover feasibility study will evaluate the therapeutic value of adding pacing from the left ventricular lead to Left Bundle Branch Area …

Heart FailureSystolic Bundle Branch Block, Left

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Medtronic Cardiac Rhythm and Heart FailureNCT07526896

Phase 1

Open-label Randomized, Three-fold Cross-over, Single-center Interaction Study to Investigate the Influence of Multiple Doses of Acetylsalicylic Acid (ASA) (Aspirin) on the Pharmacodynamics of BAY 3389934 in Healthy Participants.

The study treatment BAY3389934 is under development for people with blood clotting problems that occur due to sepsis. Sepsis is a serious condition that happen…

Drug-drug Interaction

Estimated

~$500 – $11,250

Actual pay is set by the research site.

BayerNCT07652723

Phase 2

HRT-PC Trial: Hormone Recovery After Treatment for Prostate Cancer Trial. An Open-label Phase II Study of Clomiphene Citrate in Patients With Persistent Hypogonadism After ADT for Treatment of Localized Prostate Cancer

The purpose of this phase II trial is to assess the clinical utility of clomiphene citrate for the augmentation of testosterone in prostate cancer survivors wh…

Prostate Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of NebraskaNCT07882862

Bicuspid Aortic Valve and Ascending Aortic Aneurysm Registry

The purpose of this registry is to gather information on patients with bicuspid aortic valve disease.

Bicuspid Aortic Valve

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MichiganNCT01756222

Phase 1

Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for the Treatment of Lupus

This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells f…

Lupus

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Foundation for Orthopaedics and Regenerative MedicineNCT05018858

Observational

Comparing Two Social Needs Assistance Interventions to Improve Health Among Hospitalized Children

The goal of this clinical trial is to determine the best way to help families access social and economic support services in order to improve children's health…

Social NeedsHealth-Related Social NeedsSocial Determinants of Health (SDOH)+3 more

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT07687238

Phase 2

A Phase 2 Study to Assess ADX-038 in Participants With Complement-Mediated Kidney Disease

This Phase 2 study is designed to assess the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of ADX-038 in adults with complement-mediated ki…

IgANC3GComplement-mediated Kidney Disease+2 more

Estimated

~$75 – $2,800

Actual pay is set by the research site.

ADARx Pharmaceuticals, Inc.NCT06989359

Phase 3

A Phase 3, Multicenter, Randomized, Open-Label Trial Investigating the Safety, Tolerability and Efficacy of Palopegteriparatide Administered Subcutaneously Daily at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism

This trial has a treatment duration of 78 weeks and will include adult participants already on treatment with palopegteriparatide at doses at or greater than 3…

HypoparathyroidismEndocrine System DiseasesParathyroid Diseases

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Ascendis Pharma Bone Diseases A/SNCT07081997

Phase 1

Phase I Study of Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors in Participants With Metastatic Solid Tumors With KRAS G12V Mutations

This phase I trial studies the side effects and best dose of autologous CD8+ and CD4+ transgenic T cells expressing high affinity KRASG12V mutation-specific T …

Non-small Cell Lung CancerPancreas CancerColon Cancer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Fred Hutchinson Cancer CenterNCT06043713

Phase 2

A Phase 2 Posology Study With Long-Term Extension in Participants With Well-Controlled Recurrent Pericarditis to Evaluate the Efficacy and Safety of Transition Regimens to KPL-387 Monotherapy From Standard Therapies

The primary objective of this study is to characterize the efficacy and safety of dosing regimens used to transition from prior pericarditis therapies to KPL-3…

Recurrent PericarditisHeart DiseasesPericarditis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Kiniksa Pharmaceuticals International, plcNCT07288216

An Observational Study of Natural Disease Progression in Participants With Macular Dystrophies Expressing a Stargardt-type Clinical Presentation

Macular dystrophies are a group of inherited eye conditions that affect the macula. The macula is in the center of the retina, the light sensitive part at the …

Stargardt DiseaseStargardt Macular DystrophyStargardt-like Macular Dystrophy

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Astellas Pharma Global Development, Inc.NCT07425574