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Efficacy of a Criteria Based Clinical Pathway for Rehabilitation of Shoulder Injuries

The goal of this clinical trial is to compare the current standard of care for rehabilitation of non-operative shoulder injuries to a novel, criteria-based app…

Shoulder PainShoulder Injuries

Estimated

~$10 – $6,250

United States Naval Medical Center, San DiegoNCT06536114

Lynch Syndrome Integrative Epidemiology and Genetics (LINEAGE)

The vision of the "Lynch syndrome INtegrative Epidemiology And GEnetics" (LINEAGE) Consortium is to collaboratively improve the lives and longevity of individu…

Lynch Syndrome

Estimated

~$10 – $750

University of Colorado, DenverNCT06582914

Early-Onset Colorectal Cancer Patients Too Young for Screening: Outcomes and Treatment Patterns

This is a population-based retrospective study using the Surveillance, Epidemiology, and End Results (SEER) registry and National Cancer Data Base (NCDB) to lo…

Colorectal Cancer

Estimated

~$10 – $750

Methodist Health SystemNCT07559825

Phase 1

A Phase I/Ib Study of Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung Cancer

This phase I/Ib trial studies the side effects and best dose of alisertib when given together with osimertinib in treating patients with EGFR-mutated stage IV …

Lung Cancer MetastaticEGFR Gene Mutation

Estimated

~$10 – $7,500

Collin BlakelyNCT04085315

Phase 2

FIREFLY-1: A Phase 2, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of the Oral Pan-RAF Inhibitor DAY101 in Pediatric Patients With RAF-Altered, Recurrent or Progressive Low-Grade Glioma and Advanced Solid Tumors

This is a Phase 2, multi center, open-label study to evaluate the safety and efficacy of Type II RAF (tovorafenib) in pediatric participants with low-grade gli…

Low-grade GliomaAdvanced Solid Tumor

Estimated

~$10 – $8,750

Day One Biopharmaceuticals, Inc.NCT04775485

Observational

Genomic Sequencing in Anatomically Normal Fetuses

This cohort study will examine the clinical utility of genomic sequencing (GS) in patients undergoing prenatal diagnostic procedures (chorionic villus sampling…

Pregnant Individuals Requesting Standard Microarray

Estimated

~$10 – $5,625

University of California, San FranciscoNCT06211348

Phase 2

Improving Detection and Outcomes in Patients With Metastatic Invasive Lobular Breast Cancer Through Novel F-18 FAPI PET Imaging

This study is a pilot clinical imaging trial of a prospective, head-to-head comparison of 18F-Fibroblast Activation Protein Inhibitor (FAPI)-74 PET/CT versus s…

Breast CancerMetastatic Invasive Lobular Breast Cancer

A Phase I Study of Zanzalintinib With Pembrolizumab and Cetuximab in Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck

This Phase I clinical trial evaluates the safety, tolerability, and optimal dosing of Zanzalintinib in combination with Pembrolizumab and Cetuximab in patients…

Head and Neck NeoplasmsCarcinoma, Squamous CellNeoplasm Recurrence, Local+3 more

Estimated

~$10 – $6,250

University of ChicagoNCT06912087

Phase 1

[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects

The purpose of this study is to study a radioactive tracer, a type of imaging drug that is injected into the body to see how it is taken up in sites of active …

Bacterial Infections

Estimated

~$10 – $6,250

University of PennsylvaniaNCT04263792

The Efficacy of Xeomin as a Prophylactic Therapy for Migraine in Patients With Traumatic Brain Injuries (TBIs) Versus Anomalous Health Incidents (AHIs)

This cohort study aims to compare the efficacy of Xeomin injections for migraine management in patients with a history of Traumatic Brain Injury (TBI) versus t…

MigraineTraumatic Brain InjuryAnomalous Health Incidents

Estimated

~$10 – $750

Uniformed Services University of the Health SciencesNCT07267819

Observational

Impact of a Novel HIV Peer Navigation and Overdose Prevention Intervention on Engagement in the HIV Prevention and Treatment Cascade

Through the proposed Substance Checking Outreach and Pre-Exposure Prophylaxis (PrEP) Engagement (SCOPE) study, the investigators will design and evaluate an ov…

HIV Infections

Estimated

~$10 – $5,625

Johns Hopkins Bloomberg School of Public HealthNCT05977881

Chronic Postsurgical Pain in Cerebral Palsy

The study purpose is to document the typical trajectory of perioperative pain experience in Cerebral Palsy (CP) and to identify important predictive factors fo…

Cerebral PalsyChronic Post Surgical Pain

Estimated

~$10 – $1,125

Chantel BurkittNCT05764681