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A Phase 3, Randomized, Open-label Study of Raludotatug Deruxtecan (MK-5909, R-DXd) Maintenance Treatment With or Without Bevacizumab Versus Standard of Care in Participants With Newly-Diagnosed Advanced Non-HRD-Positive Ovarian Cancer Following First-line Platinum-based Chemotherapy (ENGOT-ov102/MITO/GOG-3141/ REJOICE-Ovarian 04)

Researchers are looking for new ways to treat ovarian cancer (OC). Current treatment for OC may start with surgery to remove as much of the cancer as possible.…

Ovarian CancerOvarian NeoplasmsPeritoneal Cancer+1 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07776691

Phase 1

A Phase 1, Randomized, Double-Blind, Single Dose Escalation Study to Assess the Safety and Tolerability of Transforaminal Epidural Administration of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy

The purpose of this study is to evaluate the safety and tolerability of C-1101 administered as a single dose, transforaminal epidural injection compared to ste…

Lumbosacral Radicular PainSciatic RadiculopathySciatic Leg Pain+3 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Consano BioNCT07264270

Remote eligible

AI-Enabled Wearable Monitoring for Detection of Postpartum Depression and Anxiety

The goal of this observational study is to examine whether passively collected wearable data can be used to predict onset and severity of postpartum depression…

Postpartum Depression (PPD)Postpartum Anxiety

Estimated

~$10 – $750

Actual pay is set by the research site.

University of HawaiiNCT07866053

Phase 3

A Phase 3, Randomized, Open-Label Study of Linvoseltamab Versus Daratumumab in Participants With Smoldering Multiple Myeloma at High Risk of Developing Multiple Myeloma

This study is researching an experimental drug called linvoseltamab (also called "study drug") compared to another drug called daratumumab, in participants wit…

High Risk Smoldering Multiple Myeloma (HR-SMM)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Regeneron PharmaceuticalsNCT07393282

Observational

Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions (TURBO)

The goal of this clinical trials is to demonstrate the safety and effectiveness for the RapidPulseTM Aspiration System in patients experiencing acute ischemic …

Acute Ischemic Stroke

Estimated

~$10 – $1,050

Actual pay is set by the research site.

RapidPulse, IncNCT06029491

Phase 2

A Phase II Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed or Refractory CD10-Negative Diffuse Large B-Cell Lymphoma (DLBCL) and High-Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements (HGBCL-DH-BCL2)

This phase II trial tests how well venetoclax, ibrutinib, prednisone, obinutuzumab, and Revlimid® (ViPOR) works in treating patients with CD10 negative diffuse…

High Grade B-Cell Lymphoma With MYC and BCL6 RearrangementsRecurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type+12 more

Estimated

Phase 1

A Phase I, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors Harboring Microsatellite Instability (MSI) and/or Deficient Mismatch Repair (dMMR)

This is a first-in-human, Phase I, open-label, multicenter, dose-escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, ph…

Advanced Solid TumorsColorectal Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Vividion Therapeutics, Inc.NCT06004245

Phase 2

A Phase 2, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of Safusidenib Erbumine in Participants With Isocitrate Dehydrogenase 1 (IDH1)-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease

This study will include up to 40 participants with Grade 2 or Grade 3 IDH1-mutant glioma who have undergone surgery and received vorasidenib as their only trea…

Grade 2 IDH1-mutant GliomaGrade 3 IDH1-mutant GliomaGlioma+5 more

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Nuvation Bio Inc.NCT07703436

An Investigation of the Role of Germ-Line Mutations in Cancer Predisposition, Tumor Biology, and Response to Treatment

This research trial studies germ-line mutations in blood and saliva samples from patients with cancer. Studying samples of blood and saliva from patients with …

Malignant Neoplasm

Estimated

~$10 – $750

Actual pay is set by the research site.

Jonsson Comprehensive Cancer CenterNCT02280161

Phase 1

Topical Insulin for Glaucoma and Optic Neuropathies

The purpose of this Phase 1 trial is to determine the safety over 1-2 months of topic sterile human recombinant insulin on subjects with optic neuropathies (gl…

Glaucoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Stanford UniversityNCT05206877

Phase 2

Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer (MAPPER)

This is an exploratory phase II interventional study that initiates standard-of-care anti-estrogen treatment preoperatively for 4-12 weeks (+/- 2 weeks).

Breast Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Medical College of WisconsinNCT06361940

Observational

Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing

This 2x2 randomized crossover feasibility study will evaluate the therapeutic value of adding pacing from the left ventricular lead to Left Bundle Branch Area …

Heart FailureSystolic Bundle Branch Block, Left

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Medtronic Cardiac Rhythm and Heart FailureNCT07526896