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Randomized Trial of Hydrus Microstent Versus Goniotomy

The goal of this clinical trial is to evaluate the comparative efficacy and safety of Hydrus Microstent, incisional goniotomy, and excisional goniotomy when co…

GlaucomaGlaucoma, Open-Angle

Estimated

~$10 – $7,500

Massachusetts Eye and Ear InfirmaryNCT06289491

Phase 2

Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED

To Determine the feasibility, compliance and adherence to PreFED intervention in resectable melanoma patients initiating neoadjuvant Ipi/Nivo.

Melanoma

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT06548789

Observational

PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes

PTSD is common among Veterans with serious mental illness (SMI). Co-occurring PTSD and SMI lead to poorer mental health and physical functioning than either di…

Stress Disorders, Post-Traumatic; Mental Disorders

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT05674617

Phase 2

Phase 2 Randomized Placebo-controlled, Double-blind, Parallel Study to Assess the Safety and Efficacy of an Oral Marijuana-Based Investigational Medical Product to Treat Anxiety in Adults With Autism Spectrum Disorder (ASD)

The goal of this clinical trial is to learn if drug ABC works to treat severe asthma in adults. It will also learn about the safety of drug ABC. The main quest…

Autism Spectrum DisorderAnxiety

Estimated

~$10 – $7,500

Southwest Autism Research & Resource CenterNCT06526208

Observational

Changing the View of Pain: Using Virtual Reality As Adjunctive Therapy for Sickle Cell Pain in Pediatric Patients

The goal of this randomized control clinical trial is to learn if virtual reality can be used to treat sickle cell pain in children. The main questions it aims…

Sickle Cell DiseaseVaso-occlusive Pain Episodes

Estimated

~$10 – $6,250

Louisiana State University Health Sciences Center in New OrleansNCT06773715

Phase 4

The Efficacy of Continuous Intercostal Nerve Blocks in the Treatment of Patients With Multiple Rib Fractures

This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/o…

Rib Fractures

Estimated

~$10 – $7,500

Zachary WarrinerNCT05642026

Use of Whole Exome Sequencing/Whole Genome Sequencing in the Plain Communities

This study is designed to utilize whole exome and whole genome sequencing techniques to identify underlying genetic causes for undiagnosed disorders in the Pla…

Undiagnosed Disease

Estimated

~$10 – $750

University of PittsburghNCT02927158

Phase 2

A Phase 2, Randomized, Open Label Study of AMDX-2011P as a Retinal Tracer in Participants With Primary Open Angle Glaucoma

The purpose of this research study is to assess the ability of AMDX- 2011P to identify amyloid deposits in the retina of participants with Primary Open Angle G…

Primary Open Angle Glaucoma

Estimated

~$10 – $8,750

Amydis Inc.NCT06223048

Phase 2

A Phase 2 Randomized Trial of Remodeling Intestinal Microbiota Using Fecal Microbiome Transplant (FMT) Among Recipients of Chimeric Antigen Receptor T Cells (CAR T)

This phase II trial tests how well fecal microbiome transplantation works to remodel intestinal microbiota for patients with lymphoma that has come back after …

Recurrent Diffuse Large B-Cell LymphomaRecurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 RearrangementsRecurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma+3 more

Estimated

~$10 – $6,250

City of Hope Medical Center

Investigating Periprosthetic Fracture Culture Positivity in Patients With Hip and Knee Arthroplasties

This study aims to improve how doctors diagnose infections in patients with broken bones around joint replacements. Currently, there are no clear guidelines to…

Periprosthetic Fracture Around Prosthetic Joint Implant

Estimated

~$10 – $750

University of ChicagoNCT06952738

Making Intergenerational Connections Through Arts

The purpose of the study is to evaluate the impact on older adults' wellbeing of participating in a 10-week conversation about arts and culture with an interna…

Older Adults

Estimated

~$10 – $750

University of Alabama at BirminghamNCT05986149

Observational

The Role of Continuous Passive Motion in Pain Control of Patients Undergoing Operative Management of Isolated Acetabular Fractures, Supracondylar Femur Fractures, or Tibial Plateau Fracture: A Comparative Study

The investigators will directly compare the visual analog scale scores and narcotic pain medication requirements in the patients who have continuous passive mo…

Fractures, Bone

Estimated

~$10 – $5,625

University of CincinnatiNCT04389749