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27,069 recruiting studies available now

PRISM: Phase 1b of Retifanlimab and Ruxolitinib In Solid Malignancies Progressing on Prior Checkpoint Inhibition

The goal of this clinical trial is to learn what dose of ruxolitinib can be given safely together with retifanlimab in patients with metastatic renal cell carc…

Non Small Cell Lung CarcinomaRenal Cell Carcinoma

Estimated

~$10 – $6,250

University of California, San DiegoNCT07219576

Observational

Prospective Randomized Controlled Trial on the Effects of Almond on Facial Skin Collagen and Wrinkles

Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal w…

Collagen DegenerationWrinklePigmentation+1 more

Estimated

~$10 – $7,500

Integrative Skin Science and ResearchNCT06074276

Observational

Use of Paired Non-Invasive Vagus Nerve Stimulation in Rehabilitation of Adolescents With Cerebral Palsy: An Open Label Safety Feasibility Trial

This is an open-label safety and feasibility trial evaluating the use of paired non-invasive vagus nerve stimulation (VNS) and upper extremity (UE) rehabilitat…

Cerebral Palsy

Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT07394608

Phase 3

A Phase 3, Double Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Setmelanotide in Patients With Acquired Hypothalamic Obesity

This is a sub-study of Study RM-493-040 (NCT05774756). The goal of this sub-study is to learn how well Setmelanotide works to improve weight reduction, hunger…

Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more

Estimated

~$10 – $8,750

Rhythm Pharmaceuticals, Inc.NCT06760546

Phase 2

Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial

The goal of this short term prospective Phase II study is to compare the effects of two alternate daily doses of zinc (25 and 40 mg/day) in 34 randomly assigne…

Sickle Cell Disease

Estimated

~$10 – $5,625

University of California, San FranciscoNCT06260891

Phase 3

A Pilot Study to Evaluate Barhemsys for the Prevention of Postoperative Nausea And Vomiting in the Bariatric Surgery Population

To assess the effectiveness of Amisulpride to treat Post Operative Nausea and Vomiting (PONV) and to assess the effectiveness of Amisulpride to prevent PONV fo…

Post Operative Nausea and Vomiting

Estimated

~$10 – $7,500

Benaroya Research InstituteNCT06585540

Evaluating the Retinal and Choroidal Microvasculature and Structure Using Multimodal Retinal and Choroidal Imaging in Neurodegenerative Disease: iMIND Research Study

This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield …

Alzheimer's DiseaseMild Cognitive ImpairmentParkinson's Disease+12 more

Estimated

~$10 – $750

Duke UniversityNCT03233646

Genetic Epidemiology of Lymphoproliferative Disorders

Blood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and t…

Lymphoma, Non-HodgkinLeukemia, Lymphocytic, Chronic, B-CellLymphoma, B-Cell+2 more

Estimated

~$10 – $750

Mayo ClinicNCT00626496

A Multi-Site Prospective, Single-Arm, Observational Study On The Accuracy Of Whole Body Magnetic Resonance Imaging (Wb-Mri) Screening To Predict Clinically Significant Diagnoses In General Population Subjects Interested In Proactive And Advanced General Preventive Healthcare.

This is a prospective, single-arm, observational study capturing data from whole-body magnetic resonance imagining (WB-MRI) from up to 100,000 male and female …

CancerMetabolic DiseaseAneurysm+1 more

Larotrectinib to Enhance RAI Avidity in Patients With Differentiated Thyroid Cancer Harboring NTRK Fusions (LANTERN)

Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced …

Differentiated Thyroid CancerPediatric CancerCancer+1 more

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT05783323

Phase 2

Daily-Adaptive Stereotactic Body Radiation Therapy for Biochemically Recurrent, Radiologic Apparent Prostate Cancer After Radical Prostatectomy

There is significant, proven use of radiation for recurrent prostate cancer after surgical resection. This treatment typically is delivered over seven and a ha…

Recurrent Prostate Cancer After Surgery

Estimated

~$10 – $6,250

University of RochesterNCT05946824

Phase 4

Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors: Pharmadodynamic Comparison Between Prasugrel and Ticagrelor Monotherapy. The Switching Antiplatelet -7 (SWAP-7) Study

Ticagrelor currently represents the most tested and commonly used P2Y12 inhibitor monotherapy following percutaneous coronary intervention. The purpose of this…

Coronary Artery Disease

Estimated

~$10 – $6,250

University of FloridaNCT06691191