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27,132 recruiting studies available now

VenBom: A Phase 1 Study of Bomedemstat (IMG-7289), a Novel Inhibitor of Lysine-Specific Demethylase 1 (LSD1), in Combination With Venetoclax in Adult Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)

This study aims to learn about the safety, tolerability, and different dose levels' safety profiles of Venetoclax and Bomedemstat (VenBom) combination therapy …

Acute Myeloid LeukemiaRefractory Acute Myeloid LeukemiaAcute Myeloid Leukemia, in Relapse

Estimated

~$10 – $7,500

Terrence J Bradley, MDNCT05597306

Neurobiologic, Immunologic, and Rheumatologic Markers in Youth With PANS

This study is an investigation of the neurologic, immunologic, and rheumatologic markers of Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS). PANS is a c…

Pediatric Acute-Onset Neuropsychiatric SyndromePediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal InfectionsPANS+1 more

Estimated

~$10 – $750

Stanford UniversityNCT02889016

The Embryo Health Study: Prospective Longitudinal Analysis of PGT-P

This study intends to determine the patients' perception and motivation to obtain additional information on their preimplantation embryos' risks of polygenic d…

InfertilityHereditary Diseases

Estimated

~$10 – $1,050

Genomic Prediction Inc.NCT04528498

Observational

A Prospective, Randomized, Multi-Center Study to Assess the Safety and Performance of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers (DBX or Grafton) Mixed With Local Autograft in Patients Undergoing One to Two-Level Instrumented Posterolateral Lumbar/Thoracolumbar Fusion (PLF)

This is a phase IV post-marketing study for MagnetOs Easypack Putty. MagnetOs Easypack Putty is a synthetic bone graft extender product that is routinely used …

Degenerative Disc DiseaseSpine FusionBack Pain

Estimated

~$10 – $8,750

Kuros Biosurgery AGNCT04679844

Observational

NearWave Optical Molecular Monitoring for Predicting Complete Pathological Response (pCR) to Neoadjuvant Chemotherapy (NAC) in Breast Cancer Patients

The purpose of this study is to assess the feasibility of the NearWave optical molecular monitoring system for monitoring therapy progression and predicting pa…

Breast CancerHER2-positive Breast CancerTNBC - Triple-Negative Breast Cancer+2 more

Estimated

~$10 – $6,250

Indiana UniversityNCT06744465

Phase 1

Phase 1 Imaging Study of 68Ga-R10602-101 in Hormone Receptor-Positive Breast Cancer

A phase 1 imaging study of 68Ga-R10602 in hormone-receptor positive breast cancer.

Locoregionally Recurrent Hormone-receptor Positive Breast CancerMetastatic Hormone Receptor Positive Breast CancerHormone Receptor Positive Breast Adenocarcinoma

Estimated

~$10 – $7,500

Radionetics OncologyNCT06745804

ESCALATE: Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic"…

Complex AneuploidyChaotic Aneuploidy

Estimated

~$10 – $1,125

Shady Grove Fertility Reproductive Science CenterNCT07227116

A Prospective, Observational, Long-Term Follow-Up (LTFU) Study to Evaluate the Long-Term Safety of the Krystal Biotech, Inc. Gene Therapy Backbone Products Using HSV-1 Backbone

The main objective of this prospective, observational, long-term follow-up (LTFU) study is to evaluate the long-term safety profile of the gene therapy product…

Dystrophic Epidermolysis BullosaRecessive Dystrophic Epidermolysis BullosaDominant Dystrophic Epidermolysis Bullosa

Estimated

~$10 – $1,050

Krystal Biotech, Inc.NCT04917887

Phase 1

A Phase 1 Study of the Safety and Efficacy of CRX100 as Monotherapy and in Combination With Pembrolizumab in Advanced Solid Malignancies

This clinical study is an open-label, Phase 1, dose-escalation study to determine the safety, tolerability, and efficacy of the drug product produced by Admini…

Solid Tumor, AdultTriple Negative Breast CancerColorectal Cancer+6 more

Estimated

~$10 – $8,750

BioEclipse TherapeuticsNCT04282044

Observational

Brain Volume and Cardiac Function in Heart Failure

Patients with heart failure (HF) exhibit greater structural brain alterations and higher dementia risks than the general population. Neural atrophy in nearly e…

Heart Failure

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT06623344

Observational

Pericardiotomy in Cardiac Surgery Trial

PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or f…

Atrial FibrillationAtrial FlutterCardiac Events

Estimated

~$10 – $7,500

Population Health Research InstituteNCT06486636

Observational

Development Of a Virtual Stress Inoculation Training (SIT) Platform and Mobile Health App

The purpose of this study is to demonstrate the feasibility and utility of SIT delivered asynchronously (self-paced) via fully virtual platform with and withou…

PTSDTrauma and Stressor Related DisordersTraumatic Brain Injury

Estimated

~$10 – $6,250

The University of Texas Health Science Center, HoustonNCT06494319