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Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain

To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chroni…

Chronic PainPERIPHERAL NEUROPATHYOccipital Neuralgia+11 more

Estimated

~$10 – $750

Yale UniversityNCT07639060

Phase 3

FORAGER-2: A Phase 3, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Vepugratinib Combined With Enfortumab Vedotin and Pembrolizumab in Adults With Untreated Locally Advanced or Metastatic Urothelial Carcinoma With an FGFR3 Genetic Alteration

The purpose of this study is to test a new medicine, vepugratinib, in comparison with placebo, to see if it is safe and can help people with a bladder cancer t…

Carcinoma, Transitional CellUrinary Bladder NeoplasmsNeoplasm Metastasis

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07218380

Observational

ColoSeal™ ICD System Anastomotic Protection Pivotal Study

The purpose of this clinical investigation is to evaluate the safety of the ColoSeal ICD System by evaluating its effectiveness in reducing the stoma creation …

Rectal Cancer Surgery

Estimated

~$10 – $8,750

Averto Medical, Inc.NCT07429110

Observational

Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses

The purpose of this study is to characterize proprioceptive sensations in the missing limb of upper limb amputees using nerve stimulation, and to develop advan…

Upper Limb Amputees

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT04947462

Phase 2

Phase II Study of Cytarabine + Daunorubicin (7 + 3) + Gemtuzumab Ozogamicin vs. Cytarabine + Daunorubicin (7 + 3) + Venetoclax for the Treatment of Newly Diagnosed Core Binding Factor Acute Myeloid Leukemia (CBF-AML) in Younger Adults: A MyeloMATCH Substudy

This phase II MYELOMATCH treatment trial compares the effect of venetoclax to gemtuzumab ozogamicin, when given with cytarabine and daunorubicin ("7+3" regimen…

Core Binding Factor Acute Myeloid Leukemia

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06917911

Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant: A Prospective Natural History Study

Background: Hematopoietic stem cell transplant (HSCT) is a common treatment for many cancers and other illnesses. But many people who have HSCT go on to devel…

Hematopoietic Stem Cell Transplant

Estimated

~$10 – $675

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT05722210

Phase 3

A Phase 3, Randomized, Open-label, Multicenter Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) Maintenance Treatment With or Without Bevacizumab Versus Standard of Care in Participants With Newly Diagnosed Advanced Non-HRD Positive Ovarian Cancer Following First-line Platinum-based Chemotherapy (TroFuse-021/ENGOTov85/GOG-3102)

Researchers are looking for new ways to treat ovarian cancer (OC). Current treatment for OC may start with surgery to remove as much of the cancer as possible.…

Ovarian NeoplasmsOvarian Cancer

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07318558

Phase 2

The Progressive Supranuclear Palsy Clinical Trial Platform

The Progressive Supranuclear Palsy Clinical Trial Platform (PTP) is a multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investig…

Progressive Supranuclear Palsy(PSP)

Estimated

~$10 – $7,500

Adam BoxerNCT07173803

Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy Volunteers: A Phase 2 Randomized Study

Background: People with HIV take drugs to keep the amount of virus in their body low. One type of these drugs, called integrase strand transfer inhibitors (IN…

Healthy VolunteerWeight GainMetabolic Effects+1 more

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT05652478

Phase 1

Daily, Encapsulated, Green Tea Extract (GTE) to Mitigate Neuropathic Pain in Patients With Established Cancer-Associated Neuropathic Pain

The overall objective of this study is to test an intervention of green tea extract (GTE) to mitigate neuropathic pain in patients, specifically cancer survivo…

Neuropathic PainCancer Treatment

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT07682324

Phase 1

A Phase I/II, Randomized, Placebo-controlled, Multi-arm, Dose-finding Study to Evaluate the Safety, Efficacy and Immunogenicity of an Acne mRNA Vaccine Candidate in Adults With Moderate to Severe Acne 18 to 45 Years of Age

The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to…

Acne

Estimated

~$10 – $7,500

Sanofi Pasteur, a Sanofi CompanyNCT06316297

Phase 1

Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post-Acute Sequelae of SARS-CoV-2 (PD1-PASC I)

Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from an acute COVID-19 infection may continue to have symptoms that persist …

Post-Acute COVID-19 Syndrome

Estimated

~$10 – $5,625

National Institute of Neurological Disorders and Stroke (NINDS)NCT07388550