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Modulating Immune-Microbiome Axis Through High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

The purpose of this study is to determine whether high-intensity exercise and high-fiber diet are feasible and improve various health outcomes among participan…

Melanoma (Skin)Skin CancerAdvanced Melanoma

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT06298734

Observational

Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia

This study is being conducted to investigate gut-brain communication in individuals with functional dyspepsia and anorexia nervosa. The hope is that what the i…

Functional DyspepsiaAnorexia Nervosa

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT07772167

Observational

Testing an Adaptive Intervention for Peer-Supported Mobile Health for Primary Care Veterans With Psychological Distress

Many Veterans experience psychological distress including depression, PTSD, anxiety and problems with sleep and anger. Services to address these problems need …

Psychological Distress

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07507747

Phase 3

A Master Protocol for a Phase 3, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, in Participants With Recent Lower Extremity Revascularization for Symptomatic Peripheral Artery Disease (ROXI-PALISADE)

This study is researching 2 different experimental drugs called REGN7508 and REGN9933. The study is focused on people who have Peripheral Artery Disease (PAD),…

Peripheral Artery Disease (PAD)

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07318610

Phase 3

An Open-Label, Randomized, Multicenter Phase 3 Study Investigating the Efficacy and Safety of BGB-43395 Plus Letrozole Versus CDK4/6 Inhibitors (Abemaciclib, Palbociclib, Ribociclib) Plus Letrozole in Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Systemic Anticancer Treatment for Advanced or Metastatic Disease

The purpose of this study is to investigate the efficacy and safety of BGB-43395 in combination with letrozole compared with investigator's choice of cyclin-de…

HR+/HER2- Breast Cancer

Estimated

~$10 – $7,500

BeOne MedicinesNCT07492641

Phase 2

A 12-week Randomized, Participant and Investigator-blinded, Placebo-controlled, Exploratory Study in Adult Participants With Chronic Urticaria to Assess the Efficacy and Safety and Explore the Mechanism of Action of Remibrutinib (LOU064)

The purpose of this study is to explore the effect and Mechanism of Action (MoA) of remibrutinib (LOU064) vs. placebo on clinical outcomes in participants with…

Chronic Urticaria (CU): Chronic Inducible Urticaria (CINDU) and Chronic Spontaneous Urticaria (CSU)

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT06865651

Observational

Expanded Two-photon Imaging of Skin Biopsy Specimens

The goal of this study is to investigate the ability of two-photon fluorescence microscopy to evaluate dermatologic biopsies. The main questions it aims to ans…

Basal Cell Carcinoma of SkinSquamous Cell CarcinomaMelanocytic Lesion, Adult

Estimated

~$10 – $6,250

University of RochesterNCT07773688

Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization: A Single-Center Prospective Diagnostic Accuracy Study

This study evaluates whether multiparametric chest magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), performed without any contrast mater…

Solitary Pulmonary NoduleMultiple Pulmonary NodulesLung Neoplasms+1 more

Estimated

~$10 – $750

University of FloridaNCT07768046

Phase 2

A Phase 2 Randomized Trial of Caloric Restriction and Activity to Reduce Chemoresistance in B-cell Acute Lymphoblastic Leukemia

This study is for older children, adolescents, and young adults with B-cell Acute Lymphoblastic Leukemia (B-ALL). Higher amounts of body fat is associated with…

B-cell Acute Lymphoblastic LeukemiaObesity

Estimated

~$10 – $7,500

Etan OrgelNCT05082519

Phase 1

Dopamine and Sensorimotor Function in Stuttering

This study is being done to understand the effect of aripiprazole on adults who stutter. Stuttering is a disorder that affects speech fluency. This study aims …

Stuttering, Adult

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07215884

Phase 3

A Phase 3, Multicenter, Double-blind, Placebo-controlled, Randomized Withdrawal Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of Deucravacitinib in Children and Adolescents From 5 to Less Than 18 Years of Age With Active Juvenile Psoriatic Arthritis

The purpose of this study is to evaluate the drug levels, efficacy, and safety of Deucravacitinib (BMS-986165) in pediatric participants with juvenile psoriati…

Juvenile Psoriatic Arthritis

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT06869551

Phase 1

A Phase 1 First-in-Human, Open-Label Study Evaluating the Safety, Pharmacokinetics, and Efficacy of ABBV-711 as a Monotherapy or in Combination With Budigalimab (ABBV-181) in Adult Subjects With Advanced Squamous Tumors

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess safety, tolerability, ph…

Advanced Squamous Tumors

Estimated

~$10 – $7,500

AbbVieNCT07241039